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Abstract
Introduction. Posterior fossa tumors are life-threatening because small lesions can rapidly cause brainstem compression and hydrocephalus. In high-income settings, progress in imaging, microsurgery, and adjuvant therapy has improved survival, but outcomes from neurosurgical units in Cameroon remain poorly described. The aim of this study was to characterize presentation, surgical management, and early outcomes of patients operated on for posterior fossa tumors at Laquintinie Hospital in Douala. Materials and methods. We conducted a two-year retrospective descriptive study (2022–2023) including all patients with radiologically confirmed posterior fossa tumors who underwent surgery with histopathological confirmation. Demographic, clinical, imaging, operative, and early postoperative data were collected from records. Management of hydrocephalus, surgical approaches, histological type, complications, access to adjuvant treatment, and early mortality were described. Results. Ten patients were included (sex ratio 2.34, mean age 15.3 years), with a predominance of children. Raised intracranial pressure was the main presentation (9/10). Hydrocephalus required endoscopic third ventriculostomy or ventriculoperitoneal shunting in six patients, followed by suboccipital craniectomy tailored to tumor location. Histology showed pilocytic astrocytoma in six cases, ependymoma in two, medulloblastoma in one, and cerebellopontine angle arachnoid cyst in one. Three patients died: one from postoperative meningitis and septicemia and two from tumor recurrence without timely radiochemotherapy. Conclusion. Posterior fossa tumor surgery is feasible in our setting with acceptable short-term results, but infectious complications and limited access to adjuvant oncological treatment remain critical barriers to improved survival.
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References
- 1. Bartlett F, Kortmann R, Saran F. Medulloblastoma. Clin Oncol (R Coll Radiol). 2013;25(1):36-45.
- 2. Rehman AU, Lodhi S, Murad S. Morphological pattern of posterior cranial fossa tumors. Ann King Edward Med Univ. 2009;15(2):57-59.
- 3. Emara M, Mamdouh AE, Elmaghrabi MM. Surgical outcome of posterior fossa tumours: a Benha experience. Egypt J Neurosurg. 2020;35:18.
- 4. Ostrom QT, Gittleman H, Liao P, Rouse C, Chen Y, Dowling J, et al. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011. Neuro Oncol. 2014;16 Suppl 4:iv1-63.
- 5. Benzagmout M, Agharbi S, Chakour K, Chaoui ME. Dermoid cyst of the posterior fossa. Neurosciences (Riyadh). 2011;16(2):153-155.
- 6. Kamil MA, Yusuf I, Alper B, Cem A, Erol K, Erdener T. Surgical outcomes of cerebellar tumors in children. Pediatr Neurosurg. 2004;40(5):220-222.
- 7. Bray HN, Sappington JM. A review of posterior fossa lesions. Mo Med. 2022;119(6):553-558.
- 8. Due-Tønnessen BJ, Helseth E. Management of hydrocephalus in children with posterior fossa tumors: role of tumor surgery. Pediatr Neurosurg. 2002;43:92-96.
- 9. Sainte-Rose C, Cinalli G, Roux FE, Maixner R, Chumas PD, Mansour M, et al. Management of hydrocephalus in pediatric patients with posterior fossa tumors: the role of endoscopic third ventriculostomy. J Neurosurg. 2001;95(5):791-797.
- 10. Tamburrini G, Pettorini BL, Massimi L, Caldarelli M, Di Rocco C. Endoscopic third ventriculostomy: the best option in the treatment of persistent hydrocephalus after posterior cranial fossa tumour removal? Childs Nerv Syst. 2008;24(12):1405-1412.
- 11. Epstein F, Murali R. Pediatric posterior fossa tumors: hazards of the “preoperative” shunt. Neurosurgery. 1978;3(4):348-350.
- 12. Taylor WA, Todd NV, Leighton SE. CSF drainage in patients with posterior fossa tumours. Acta Neurochir (Wien). 1992;117(1-2):1-6.
- 13. Mfouapon-Ewane HB, Djoubairou B, Nassourou OH, Figuim B, Ndome T, Bikono ERA, et al. Endoscopic third ventriculostomy at Laquintinie Hospital (Douala): a report of 23 cases. Health Sci Dis. 2023;24(11).
- 14. Muzumdar D, Ventureyra EC. Treatment of posterior fossa tumors in children. Expert Rev Neurother. 2010;10(4):525
References
1. Bartlett F, Kortmann R, Saran F. Medulloblastoma. Clin Oncol (R Coll Radiol). 2013;25(1):36-45.
2. Rehman AU, Lodhi S, Murad S. Morphological pattern of posterior cranial fossa tumors. Ann King Edward Med Univ. 2009;15(2):57-59.
3. Emara M, Mamdouh AE, Elmaghrabi MM. Surgical outcome of posterior fossa tumours: a Benha experience. Egypt J Neurosurg. 2020;35:18.
4. Ostrom QT, Gittleman H, Liao P, Rouse C, Chen Y, Dowling J, et al. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011. Neuro Oncol. 2014;16 Suppl 4:iv1-63.
5. Benzagmout M, Agharbi S, Chakour K, Chaoui ME. Dermoid cyst of the posterior fossa. Neurosciences (Riyadh). 2011;16(2):153-155.
6. Kamil MA, Yusuf I, Alper B, Cem A, Erol K, Erdener T. Surgical outcomes of cerebellar tumors in children. Pediatr Neurosurg. 2004;40(5):220-222.
7. Bray HN, Sappington JM. A review of posterior fossa lesions. Mo Med. 2022;119(6):553-558.
8. Due-Tønnessen BJ, Helseth E. Management of hydrocephalus in children with posterior fossa tumors: role of tumor surgery. Pediatr Neurosurg. 2002;43:92-96.
9. Sainte-Rose C, Cinalli G, Roux FE, Maixner R, Chumas PD, Mansour M, et al. Management of hydrocephalus in pediatric patients with posterior fossa tumors: the role of endoscopic third ventriculostomy. J Neurosurg. 2001;95(5):791-797.
10. Tamburrini G, Pettorini BL, Massimi L, Caldarelli M, Di Rocco C. Endoscopic third ventriculostomy: the best option in the treatment of persistent hydrocephalus after posterior cranial fossa tumour removal? Childs Nerv Syst. 2008;24(12):1405-1412.
11. Epstein F, Murali R. Pediatric posterior fossa tumors: hazards of the “preoperative” shunt. Neurosurgery. 1978;3(4):348-350.
12. Taylor WA, Todd NV, Leighton SE. CSF drainage in patients with posterior fossa tumours. Acta Neurochir (Wien). 1992;117(1-2):1-6.
13. Mfouapon-Ewane HB, Djoubairou B, Nassourou OH, Figuim B, Ndome T, Bikono ERA, et al. Endoscopic third ventriculostomy at Laquintinie Hospital (Douala): a report of 23 cases. Health Sci Dis. 2023;24(11).
14. Muzumdar D, Ventureyra EC. Treatment of posterior fossa tumors in children. Expert Rev Neurother. 2010;10(4):525
