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Abstract
Background: Sub-Saharan Africa bears the heaviest global burden of HIV. Despite significant progress in the prevention-testing-treatment triad, persistent challenges hinder the achievement of elimination targets. Objective: To analyze the strengths and limitations of current HIV control strategies in Sub-Saharan Africa and to propose a complementary alternative focused on systemic community strengthening. Methodology: This article is a critical narrative review of scientific literature and programmatic reports from the last 10 years, focused on the sub-Saharan context. Results: Current strategies (ART, PrEP, PMTCT) are effective but face structural barriers: weak health systems, stigma, socio-economic challenges, and difficulties in retention in the care continuum. SSA's role in the global response is crucial and innovative (e.g., task-shifting models), but remains insufficiently supported. Proposal: We propose the "Test-Treat-Educate-Maintain" (T²EM) model, an integrated and decentralized approach rooted in communities. It is based on 1) strengthening self-testing and community-based testing, 2) ultra-rapid ART initiation via community health workers, 3) peer-led education cycles focused on adherence and combined prevention, and 4) a maintenance system using simplified digital follow-up (SMS) and support groups. Conclusion: The T²EM model aims to complement national strategies by improving patient accessibility, acceptability, and retention. Its implementation requires strengthened partnership between national programs, communities, and local researchers for operational evaluation.
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References
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- 16. Johnson CC, et al. Realizing the potential of HIV self-testing in sub-Saharan Africa. Afr J AIDS Res. 2021;20(1):1-8.
- 17. Koenig SP, et al. Same-day HIV testing with initiation of antiretroviral therapy versus standard care for persons living with HIV: A randomized unblinded trial. PLoS Med. 2017;14(7):e1002357.
- 18. Murray SM, et al. The impact of group-based psychotherapy on psychosocial outcomes for HIV-positive adults in sub-Saharan Africa: a systematic review. AIDS Behav. 2021;25(10):3225-3242.
- 9. Lester RT, et al. Effects of a mobile phone short message service on antiretroviral treatment adherence in Kenya (WelTel Kenya1): a randomised trial. Lancet. 2010;376(9755):1838-45.
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References
1. ONUSIDA. Rapport mondial sur le VIH 2023. Genève : ONUSIDA ; 2023.
2. WHO. Consolidated guidelines on HIV prevention, testing, treatment, service delivery and monitoring: recommendations for a public health approach. Genève : WHO ; 2021.
3. Gaolathe T, et al. Botswana's progress toward achieving the 2020 UNAIDS 90-90-90 antiretroviral therapy and virological suppression goals. PLoS One. 2021;16(3):e0246823.
4. Dzah SM, et al. Barriers to retention in care among people living with HIV in sub-Saharan Africa: a systematic review. AIDS Care. 2023;35(1):1-12.
5. Geng EH, et al. Retention in care and patient-reported reasons for undocumented transfer or stopping care among HIV-infected patients on antiretroviral therapy in Eastern Africa. AIDS. 2020;34(8):1259-1268.
6. Assefa Y, et al. Task shifting for scale-up of HIV care: evaluation of nurse-centered antiretroviral treatment at rural health centers in Rwanda. PLoS Med. 2019;16(7):e1002858.
7. The INSIGHT START Study Group. Initiation of Antiretroviral Therapy in Early Asymptomatic HIV Infection. N Engl J Med. 2015;373:795-807.
8. Saley SM, et al. Facteurs associés à la perte de vue des patients sous traitement antirétroviral à Niamey, Niger. Revue Santé Publique d'Afrique. 2022;14(2):45-52.
9. Dao S, et al. Challenges in maintaining the HIV care continuum in a referral hospital in Mali. Med Sante Trop. 2020;30(1):78-84.
10. Eakle R, et al. PrEP distribution in sub-Saharan Africa: mapping current practices and opportunities for expansion. J Int AIDS Soc. 2022;25(Suppl 1):e25909.
11. Iwu CJ, et al. Task shifting for initiation and monitoring of antiretroviral therapy for HIV-infected adults: a systematic review. J Public Health Afr. 2020;11(1):1307.
12. Myer L, et al. Prevention of mother-to-child transmission of HIV in Africa: successes and challenges. Lancet. 2019;394(10210):1716-1726.
13. Bärnighausen T, et al. Sustainability and long-term impact of global health initiatives: the case of HIV in sub-Saharan Africa. Health Aff (Millwood). 2021;40(1):154-162.
14. Kharsany ABM, Karim QA. HIV Infection and AIDS in Sub-Saharan Africa: Current Status, Challenges and Opportunities. Open AIDS J. 2016;10:34-48.
15. Remme M, et al. The cost and cost-effectiveness of gender-responsive interventions for HIV: a systematic review. J Int AIDS Soc. 2021;24(4):e25691.
16. Johnson CC, et al. Realizing the potential of HIV self-testing in sub-Saharan Africa. Afr J AIDS Res. 2021;20(1):1-8.
17. Koenig SP, et al. Same-day HIV testing with initiation of antiretroviral therapy versus standard care for persons living with HIV: A randomized unblinded trial. PLoS Med. 2017;14(7):e1002357.
18. Murray SM, et al. The impact of group-based psychotherapy on psychosocial outcomes for HIV-positive adults in sub-Saharan Africa: a systematic review. AIDS Behav. 2021;25(10):3225-3242.
9. Lester RT, et al. Effects of a mobile phone short message service on antiretroviral treatment adherence in Kenya (WelTel Kenya1): a randomised trial. Lancet. 2010;376(9755):1838-45.
20. Bango F, et al. Community-based adherence clubs for the management of stable antiretroviral therapy patients in Cape Town, South Africa: a cost-effectiveness analysis. J Acquir Immune Defic Syndr. 2020;85(4):487-494.
