TY - JOUR AU - Epee, Emilienne AU - Afetane, Ted Grimbert AU - Aboutou, Rosalie AU - Bella Assumpta, Lucienne PY - 2014/04/25 Y2 - 2024/03/28 TI - Lésions oculaires de l’onchocercose et observance au Traitement à L’Ivermectine Sous Directives Communautaires (TIDC). JF - HEALTH SCIENCES AND DISEASE JA - Health Sci. Dis. VL - 15 IS - 2 SE - Research Articles DO - 10.5281/hsd.v15i2.338 UR - https://hsd-fmsb.org/index.php/hsd/article/view/338 SP - AB - <!--[if gte mso 9]><xml> <o:OfficeDocumentSettings> <o:AllowPNG/> </o:OfficeDocumentSettings></xml><![endif]--><p class="MsoNormal" style="margin-bottom: .0001pt; text-align: justify; line-height: normal; mso-layout-grid-align: none; text-autospace: none;"><em style="mso-bidi-font-style: normal;"><span style="font-size: 12.0pt; font-family: 'Times New Roman','serif'; color: black; mso-themecolor: text1; mso-ansi-language: EN-US;" lang="EN-US">Aim:</span></em><span style="font-size: 12.0pt; font-family: 'Times New Roman','serif'; color: black; mso-themecolor: text1; mso-ansi-language: EN-US;" lang="EN-US">The aim of our study was to determine whether the ocular complications of onchocerciasis influenced the compliance with CDTI.</span></p><p class="MsoNormal" style="margin-bottom: .0001pt; text-align: justify; line-height: normal; mso-layout-grid-align: none; text-autospace: none;"><span style="font-size: 12.0pt; font-family: 'Times New Roman','serif'; color: black; mso-themecolor: text1; mso-ansi-language: EN-US;" lang="EN-US"> </span></p><p class="MsoNormal" style="margin-bottom: .0001pt; text-align: justify; line-height: normal; mso-layout-grid-align: none; text-autospace: none;"><em style="mso-bidi-font-style: normal;"><span style="font-size: 12.0pt; font-family: 'Times New Roman','serif'; mso-fareast-font-family: 'Times New Roman'; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: minor-bidi; mso-ansi-language: EN-US; mso-fareast-language: FR; mso-bidi-font-weight: bold;" lang="EN-US">Materials and methods: </span></em><span style="font-size: 12.0pt; font-family: 'Times New Roman','serif'; color: black; mso-themecolor: text1; mso-ansi-language: EN-US;" lang="EN-US">We conducted a cross-sectional descriptive study including all subjects aged 10 years or more. . The variables studied were visual acuity, type of visual impairment, gender, onchocerciasis ocular manifestations, the number of time <span style="mso-spacerun: yes;"> </span>Ivermectin was <span style="mso-spacerun: yes;"> </span>taken over the last 5 years.</span></p><p class="MsoNormal" style="margin-bottom: .0001pt; text-align: justify; line-height: normal; mso-layout-grid-align: none; text-autospace: none;"><span style="font-size: 12.0pt; font-family: 'Times New Roman','serif'; color: black; mso-themecolor: text1; mso-ansi-language: EN-US;" lang="EN-US"> </span></p><p class="MsoNormal" style="margin-bottom: .0001pt; text-align: justify; line-height: normal; mso-layout-grid-align: none; text-autospace: none;"><em style="mso-bidi-font-style: normal;"><span style="font-size: 12.0pt; font-family: 'Times New Roman','serif'; mso-fareast-font-family: 'Times New Roman'; mso-ansi-language: EN-US; mso-fareast-language: FR; mso-bidi-font-weight: bold;" lang="EN-US">Results:</span></em><span style="font-size: 12.0pt; font-family: 'Times New Roman','serif'; color: black; mso-themecolor: text1; mso-ansi-language: EN-US;" lang="EN-US">We recruited 764 patients or 1528 eyes. The number of eyes with ocular manifestations of onchocerciasis was 56 while the number of eyes without was 1472. We found a prevalence of 48% good adherence CDTI within the general population. Nevertheless the prevalence</span><span style="font-size: 12.0pt; font-family: 'Times New Roman','serif'; mso-ansi-language: EN-US;" lang="EN-US"> <span style="color: black; mso-themecolor: text1;">among cases was of 57% good compliance compared to a prevalence of 48% among controls (P = 0.28). This similarity in the pattern of taking Ivermectin between female and male was found.</span></span></p><p class="MsoNormal" style="margin-bottom: .0001pt; text-align: justify; line-height: normal; mso-layout-grid-align: none; text-autospace: none;"><span style="font-size: 12.0pt; font-family: 'Times New Roman','serif'; color: black; mso-themecolor: text1; mso-ansi-language: EN-US;" lang="EN-US"> </span></p><p class="MsoNormal" style="margin-bottom: .0001pt; text-align: justify; line-height: normal; mso-layout-grid-align: none; text-autospace: none;"><em style="mso-bidi-font-style: normal;"><span style="font-size: 12.0pt; font-family: 'Times New Roman','serif'; color: black; mso-themecolor: text1; mso-ansi-language: EN-US;" lang="EN-US">Conclusion</span></em><span style="font-size: 12.0pt; font-family: 'Times New Roman','serif'; color: black; mso-themecolor: text1; mso-ansi-language: EN-US;" lang="EN-US">:</span></p><p class="MsoNormal" style="margin-bottom: .0001pt; text-align: justify; line-height: normal; mso-layout-grid-align: none; text-autospace: none;"><span style="font-size: 12.0pt; font-family: 'Times New Roman','serif'; color: black; mso-themecolor: text1; mso-ansi-language: EN-US;" lang="EN-US">Patients with onchocerciasis ocular involvement showed better compliance to CDTI in the Littoral region. Gender is not a factor influencing compliance to CDTI in our study in contrast to some available reports in the literature. The pattern of taking Ivermectin is not a contributing factor predisposing male to onchocerciasis ocular involvement. In the absence of visual impairment, patients with onchocerciasis ocular involvement have better compliance to CDTI. <em style="mso-bidi-font-style: normal;">:</em> The presence of onchocerciasis ocular involvement seems to be a motivating factor to a better compliance to CDTI for affected patients.</span></p><p class="MsoNormal" style="margin-bottom: .0001pt; text-align: justify; line-height: normal; mso-layout-grid-align: none; text-autospace: none;"><span style="font-size: 12.0pt; font-family: 'Times New Roman','serif'; color: black; mso-themecolor: text1; mso-ansi-language: EN-US;" lang="EN-US"> </span></p><p class="MsoNormal" style="margin-bottom: .0001pt; text-align: justify; line-height: normal; mso-layout-grid-align: none; text-autospace: none;"><strong style="mso-bidi-font-weight: normal;"><em style="mso-bidi-font-style: normal;"><span style="font-size: 12.0pt; font-family: 'Times New Roman','serif'; color: black;">Keywords: Compliance, Onchocerciasis, Ivermectin , 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