Epithelioid Hemangioendothelioma of the Leg in Brazzaville
Hémangioendothéliome Épithélioïde de la Jambe à Brazzaville
DOI:
https://doi.org/10.5281/hra.v2i6.5721Keywords:
Hemangioendothelioma,, epithelioid, soft tissues, vascular tumorAbstract
RÉSUMÉ
L’hémangio-endothéliome épithélioïde (HEE) est une tumeur vasculaire à malignité intermédiaire survenant essentiellement dans l’os, les tissus mous, le poumon et le foie. Souvent considéré comme une tumeur à malignité intermédiaire entre les hémangiomes bénins et les angiosarcomes agressifs, l’HEE comporte un potentiel de récidives locales, de métastases ganglionnaires et à distance et ne s’accompagne pas fréquemment de décès dans les formes localisées, mais le pronostic est sombre dans les formes métastatiques. Nous rapportons l’observation d’un patient âgé de 37 ans, suivi dans le service d’oncologie médicale du CHU de Brazzaville pour une tumeur des parties molles de la jambe gauche, dont l’analyse histologique de la biopsie avait conclu à un hémangio-endothéliome épithélioïde. Le bilan d’extension réalisé a retrouvé des images scanographiques en faveur de localisations secondaires pulmonaires. Le projet thérapeutique avait consisté en une chirurgie réductrice suivie d’une chimiothérapie palliative mais faute de moyens financiers, le patient n’a pas bénéficié de cette prise en charge et est décédé.
ABSTRACT
Epithelioid hemangioendothelioma (EHE) is a vascular tumor, usually considered as a low-grade malignancy that occurs primarily in bone, soft tissues, lung and liver. Often considered as an intermediate malignancy tumor between benign hemangiomas and aggressive angiosarcomas, EHE has the potential for local recurrence, lymph node and distant metastasis and is not frequently accompanied by death in localized forms, but the prognosis is poor in metastatic conditions. We report the case of a 37-year-old patient, who was referred to the medical oncology department of the Brazzaville University Hospital for the management of a tumor of the soft tissues of the left leg, whose histological analysis of the biopsy had concluded to an epithelioid hemangioendothelioma. The extension assessment carried out had found secondary pulmonary locations at CT-scan. The therapeutic project had considered a tumor-reductive surgery followed by a palliative chemotherapy, but due to lack of financial ressources, the patient did not benefit from this care and died.
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Copyright (c) 2024 Bolenga Liboko Alexis Fortuné, Moyikoua Franck Régis, Litingui Mboba TM, Rissia Ferdinand, Mavoungou Kedel, Nsonde-Malanda J, Nkoua-Mbon JB
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