Bilateral Galactorrhea in Women: When Prolactin Makes Us Wander
Galactorrhée Bilatérale Chez la Femme : Quand la Prolactine Nous Fait Errer
Keywords:
Galactorrhea; hyperprolactinemia; Abidjan.Abstract
RÉSUMÉ
Introduction. La galactorrhée est un motif fréquent de consultation en gynécologie et en endocrinologie. Ses étiologies sont étroitement liées à celles des hyperprolactinémies. Nous rapportons ici un cas de galactorrhée bilatérale sans hyperprolactinémie. Observation. Mme K.M., 33ans, primigeste et primipare, étudiante, sans antécédents particuliers reçue en endocrinologie pour galactorrhée bilatérale. L’anamnèse retrouvait un accouchement 3 ans auparavant avec allaitement et sevrage du nourrisson à 9 mois sans tarissement spontané de la galactorrhée associée à une oligoménorrhée et dyspareunie, céphalées sans troubles visuels et un traitement avec 0,5mg par semaine de cabergoline institué par le gynécologue pendant un mois sans succès et interrompu. Pas de notion de prise médicamenteuse particulière. Notre examen retrouvait une obésité modérée et une galactorrhée lactescente bilatérale provoquée. L’écho mammographie et les cinq axes hypophysaires étaient sans particularités avec une prolactine à 11,23ng/ml. Nous avons retenu le diagnostic d’une galactorrhée idiopathique et la cabergoline a été réintroduite à 0,5mg par semaine avec réduction de l’écoulement au bout de 2 mois de traitement. Discussion. La galactorrhée idiopathique n’est pas rare mais reste un diagnostic d’exclusion qui devra être évoqué après un bilan étiologique exhaustif normal, notamment interrogatoire, examen physique et bilan paraclinique permettant d’éliminer les autres causes.
ABSTRACT
Introduction. Galactorrhea is a frequent reason for consultation in gynecology and endocrinology. Its etiologies are closely related to those of hyperprolactinemia. We report here a case of bilateral galactorrhea without hyperprolactinemia. Observation. Mrs K.M., 33 years old, primigravida and primiparous, student, with no particular history, was seen in endocrinology for bilateral galactorrhea. The history revealed a childbirth 3 years earlier with breastfeeding and weaning of the infant at 9 months without spontaneous cessation of the galactorrhea associated with oligomenorrhea and dyspareunia, headaches without visual disorders and a treatment with 0,5mg per week of cabergoline instituted by the gynecologist during one month without success and interrupted. No notion of particular medication. Our examination revealed moderate obesity and bilateral induced lactescent galactorrhea. The ultrasound mammography and the five pituitary axes were without particularities with a prolactin at 11,23ng/ml. We retained the diagnosis of idiopathic galactorrhea and cabergoline was reintroduced at 0,5mg per week with reduction of discharge after 2 months of treatment. Discussion. Idiopathic galactorrhea is not uncommon but remains a diagnosis of exclusion that should be evoked after an exhaustive normal etiological workup, including questioning, physical examination and paraclinical workup to eliminate other causes.
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Copyright (c) 2024 Jocelyne Danho, Koné Famoussa, Nesta Ziza, Assita Yao, Adelaïde Hué, Kouassi Franck, Anselme N’Guessan, Jocelyne Lecadou, Pierre Koffi-Dago, Jacko Abodo, Adrien Lokrou
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