Prevalence and Determinants of Hyperuricemia in Type 2 Diabetes Mellitus Patients in Bouaké
Prévalence et Déterminants de l’Hyperuricémie chez le Patient Diabétique de Type 2 à Bouaké
DOI:
https://doi.org/10.5281/hra.v2i7.5657Keywords:
hyperuricemia, type 2 diabetes, Bouaké University Hospital Center, Côte d'IvoireAbstract
RÉSUMÉ
Introduction. L'hyperuricémie est un facteur de risque indépendant pour le développement du diabète de type 2 et est associée à une augmente de la morbimortalité chez les patients diabétiques. Le but de cette étude était de déterminer la prévalence et les déterminants de l'hyperuricémie chez les patients diabétiques de type 2 suivis au Centre Hospitalier de Bouaké. Méthodes. Il s'agissait d'une étude rétrospective à visée descriptive réalisée sur 6 mois au CHU de Bouaké. L'hyperuricémie a été définie comme un taux d'acide urique sérique >70 mg/l pour les hommes et >60 mg/l pour les femmes. Résultats. Un total de 102 dossiers de patients diabétiques de type 2 au cours du suivi ont été recrutés dans l'étude. La prévalence de l'hyperuricémie était de 29,4% (n=30) dans la population étudiée. L'âge moyen des patients était de 61,5 ± 9,7 ans et le sex-ratio de 0,85. L'indice de masse corporelle (IMC) moyen était de 26,9 ± 6,9 kg/m². La durée moyenne du diabète était de 4,7 ± 6,9 ans et 67,6% des patients souffraient d'hypertension artérielle. L’obésité abdominale retrouvée dans 48% des cas. L’hémoglobine A1c moyenne était de 9,5 ± 3% avec plus des deux tiers des patients qui présentaient un diabète déséquilibré. L’hypertension artérielle systolique et l’hypertriglycéridémie étaient statistiquement associés à l’hyperuricémie, contrairement aux autres variables indépendantes. Conclusion. La prévalence de l'hyperuricémie était relativement élevée chez les patients diabétiques de type 2. L'hyperuricémie était significativement associée à l’hypertension artérielle systolique et l’hypertriglycéridémie.
ABSTRACT
Introduction. Hyperuricemia is an independent risk factor for the development of type 2 diabetes and is associated with increased morbidity and mortality in diabetic patients. The aim of this study was to determine the prevalence and determinants of hyperuricemia in type 2 diabetic patients followed at Bouaké University Hospital Center. Materials and methods. This was a retrospective descriptive study conducted over 6 months at Bouaké University Hospital. Hyperuricaemia was defined as a serum uric acid level >70 mg/l for men and >60 mg/l for women. Results. A total of 102 records of patients with type 2 diabetes during follow-up were enrolled in the study. The prevalence of hyperuricaemia was 29.4% (n=30) in the study population. The mean age of the patients was 61.5 ± 9.7 years and the sex ratio was 0.85. The mean body mass index (BMI) was 26.9 ± 6.9 kg/m². The mean duration of diabetes was 4.7 ± 6.9 years, and 67.6% of patients had arterial hypertension. Abdominal obesity was found in 48% of cases. The mean haemoglobin A1c was 9.5 ± 3%, with more than two-thirds of patients presenting with unbalanced diabetes. Systolic arterial hypertension and hypertriglyceridaemia were statistically associated with hyperuricaemia, unlike the other independent variables. Conclusion. The prevalence of hyperuricaemia was relatively high in type 2 diabetic patients. Hyperuricaemia was significantly associated with systolic hypertension and hypertriglyceridaemia.
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Copyright (c) 2024 Famoussa Kone, Kadidiata Hamed Touré, Lauret Kouassi, Jean Kévin Acho, Gnadou Stéphane Kény Yapa, Bansimba Stéphane Rodney Nzonzy, Oumar Naponon Keita, Salifou Koné, Bourhaima Ouattara
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