EVALUATION OF PHYTOCHEMICAL SCREENING AND IN VITRO ANTIOXIDANT ACTIVITY OF ETHANOLIC AND HYDROETHANOLIC EXTRACTS OF THE FRUITS AND TWIGS OF FICUS OVATA VAHL (MORACEAE

Mametou Fouondo, B. C Nyangono, Charles Fokunang

Abstract


Introduction: The use of medicinal plant is quasi-general throughout the continent; however some of the plants reputed in the indigenous system of medicine are not scientifically established for their activities. The study such as ethno medicine keenly represents one of the best avenues in searching new economic plants for medicine. The current study examined the phytochemicals, in vitro antioxidant activities of the Hydroethanolic and ethanolic extracts of twigs and fruits of Ficus ovata.

Materials and methods: These extracts were prepared by maceration of the twigs and fruits separately in ethanol or hydroethanolic solvent for 48hours. Then used for the phytochemical analysis and antioxidant potential screening in vitro which include polyphenol content test and the DPPH antiradical test.

Results:The Phytochemical screening revealed the presence of alkaloids, tannins, saponins, glycosides, phenols and flavanoids in all extracts except phlobatannin that was absent in the fruit extracts. Fruits extracts had the highest polyphenol content (EF= 718.142 ± 12.910mg CatEq vs HF= 486.876 ± 8.606 mg CatEq; P< 0.05) and the best DPPH antiradical scavenging effect (IC50; EF= 2.7mg/ml, HF=0.70mg/ml) compared to twigs (P< 0.05).

Conclusion: our findings indicate that Ficus ovata content most bioactive phytochemicals use in traditional medicine and scavenging antiradical effects which could be essential for the improvement of cardiovascular related diseases.

 


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