Journal Description

EISSN: 2309-6535 (online) ISSN: 1684-2782
Health Sciences and Disease, is an open source, peer reviewed medical journal that covers all aspects of medicine, pharmacy, biomedical and health sciences, including public health and societal issues. It is an online first publication, which means that all the publications articles appear on the website before being included in the print journal. The papers are published in full on the website, with open access. Our vision is to be the leader medical journal in our region. Our mission is to inform and educate all the health professionals and to promote constructive debate on health issues that matter in the management not only of diseases but of health as a whole.
Health Sciences and Disease is the official publication of the Faculty of Medicine and Biomedical Sciences of the University of Yaounde I. Its team is based in Yaounde (Cameroon).

Health Research in Africa (HRA) is a partner journal of HSD.

Vol. 26 No. 5 (2025): Health Sciences and Disease

Published: 30 April 2025

Please, Download the Front Cover Page Here

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DOI: https://doi.org/10.5281/hsd.v26i5.6674

Please, Download the Full Contents Page Here

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DOI: https://doi.org/10.5281/hsd.v26i5.6675

The Dean's Adress
Le Mot du Doyen

Ngo Um Esther

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Scientific programme at a glance

Ngo Um Esther

PDF (Français (Canada))

DOI: https://doi.org/10.5281/hsd.v26i5.6676

Preventive Properties of a Polyherbal (Annona muricata L, Piper capense, Passiflora edulis, and Propolis) Against Breast Cancer in Wistar Rats
Propriétés Préventives d'une Association de Plantes (Annona muricata L, Piper capense, Passiflora edulis et Propolis) contre le Cancer du Sein chez les Rats Wistar

Lamissa N, Nkuimi KO, Fomat BP, Mendimi NJM, Zingue S

PDF (Français (Canada))

DOI: https://doi.org/10.5281/hsd.v26i5.6624

Arrimage Moléculaire des Triterpènes Isolés de l'Écorce de Vernonia Conferta sur le Cancer de la Peau Médié par les Protéines MRCK Alpha et Bêta
Molecular Docking of Triterpenes Isolated from the Bark of Vernonia conferta on Skin Cancer Mediated by MRCK Alpha and Beta Proteins

Soppo LCV, Nko’o MHJ, Foumane MJS, Ngo-Nyobe JC, Ngah DK, Nyangono NM, Kack NSNL, Benga MFC, Ndzié MBP, Obono FMP, Emanda EMG, Ndom JC, Nnanga Nga, Mpondo MEA, Foumane P

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DOI: https://doi.org/10.5281/hsd.v26i5.6626

Control of Quality Parameters of Hydroquinone, Hydrocortisone and Clobetasol Propionate by High Performance Liquid Chromatography (HPLC) for Lightening Cosmetic Products Marketed in the City of Yaoundé
Contrôle des Paramètres Qualité de l’Hydroquinone, l’Hydrocortisone et du Clobétasol Propionate par Chromatographie Liquide Haute Performance (HPLC) pour des Produits Cosmétiques Éclaircissants Commercialisés dans la Ville de Yaoundé

Nyangono NM, Fouelefack MY, Mbole J, Soppo LCV, Foumane MS, Aba’a M, Nko’o L, Ndjitoyap, Nnanga Nga, Ngombi AM

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DOI: https://doi.org/10.5281/hsd.v26i5.6625

Anticancer Potential of Some Plants from the Cameroon Pharmacopoeia
Potentiel Anticancéreux de Quelques Plantes de la Pharmacopée Camerounaise

Mbosso Teinkela Jean Emmanuel

PDF (Français (Canada))

DOI: https://doi.org/10.5281/hsd.v26i5.6627

Formulation of a syrup based on Eucalyptus leaves
Formulation d’un Sirop à Base de Feuilles d’Eucalyptus

Foumane Maniepi NJS, Benga MC, Soppo LV, Nzie Maniben P, Mbolé MJ, Nyangono DM, Minyem NAP, Aba’a DM, Nko’o JM, Obono FP, Ngolsou F, Emanda M, Nnanga Nga, Ze Minkande J

PDF

DOI: https://doi.org/10.5281/hsd.v26i5.6630

Study of a Diet Drink based on Solanum Sp. fruit
Étude d’une Boisson Diététique à Base de Fruits de Solanum Sp

Foumane Maniepi NJS, Bidjogo EJ, Nko’o JM, Soppo LV, Benga MC, Mbolé MJ, Minyem NAP, Nyangono DM, Aba’a DM, Obono FP, Nzie Maniben P, Golson F, Nnanga Nga, Ze Minkande J

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DOI: https://doi.org/10.5281/hsd.v26i5.6631

Operated Digestive Cancers in Cameroon: Typology and Diagnostic Staging
Cancers Digestifs Opérés au Cameroun : Typologie et Stadification au Diagnostic

Bang GA, Savom EP, Djopseu LK, Chasim CB, Moto GB, Essomba A

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Survival and Quality of Life of Patients (assessed with EORTC QLQ C30) After Rectal Cancer Surgery in a Low-Income Country: A Study in Cameroon, Sub-Saharan African Region
Survie et Qualité de Vie des Patients (Évaluée Avec l'EORTC QLQ C30) Après une Chirurgie du Cancer du Rectum dans un Pays à Faible Revenu : Une Étude au Cameroun, Région d'Afrique Sub-Saharienne

Bang GA, Savom EP, Moto GB, Fayam JY, Essomba A, Sosso MA

PDF

DOI: https://doi.org/10.5281/hsd.v26i5.6628

Indications and Results of Colonoscopies in Subjects Aged 60 and Over in Yaoundé, (Cameroon)
Indications et Résultats des Coloscopies chez les Sujets Âgés de 60 ans et Plus à Yaoundé (Cameroun)

Ndjitoyap NAW, Ntsama EMJ, Njoya MM, Dang BI, Bakelak DD, Bougha G, Talla P, Ankouane AF, Ndjitoyap NEC

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DOI: https://doi.org/10.5281/hsd.v26i5.6632

Molecular Classification of Breast Cancers Diagnosed at the Centre Pasteur in Cameroon
Classification Moléculaire des Cancers du Sein Diagnostiqués au Centre Pasteur du Cameroun

Bodo EML, Atangana PJA, Sando Z

PDF

DOI: https://doi.org/10.5281/hsd.v26i5.6633

Cytopathological Aspects of the Uterine Cervix of Pregnant Women in Yaoundé
Aspects Cytopathologiques du Col Utérin chez la Femme Enceinte à Yaoundé

Mayemi E, Ndoumba A, Ngo Pambe CJ, Ananga Noa S, Essame O, Nkegoum B

PDF

DOI: https://doi.org/10.5281/hsd.v26i5.6634

Prevalence of High-Risk Human Papillomavirus Serotypes and Confrontation with Available Vaccine Antigens: The Case of Cameroon
Prévalence des Sérotypes de Papillomavirus Humain à Haut Risque et Confrontation avec les Antigènes Vaccinaux Disponibles : Le Cas du Cameroun

Ebong CE, Nzang JL, Nyada SR, Essiben F, Tompeen I, Fouedjio JH, Fouelifack Y, Metogo J, Batoum VM, Nsahlai C, Seungue J, Dohbit SJ

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DOI: https://doi.org/10.5281/hsd.v26i5.6635

Relationship Between Tumor Infiltrating Lymphocytes (TILS) and Hormone-Sensitive (Breast and Prostate) Cancer Survival: Cases Received at Yaoundé General Hospital from 2019 to 2023
Relation entre les Lymphocytes Infiltrant la Tumeur (TILS) et la Survie au Cancer Hormono-Sensible (Sein et Prostate) : Cas Reçus à l'Hôpital Général de Yaoundé de 2019 à 2023

Atenguena OE, Zingue S, Makamte GK, Maliedje TDE, Zingue LL, Mayemi M, Mbopda NEA, Sando Z

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DOI: https://doi.org/10.5281/hsd.v26i5.6636

Impact of Oral Cryotherapy on the Occurrence of Oral Mucositis in Cancer Patients Treated with Chemotherapy
Impact de la Cryothérapie Orale sur la Survenue de la Mucite Buccale chez les Patients Cancéreux Traités par Chimiothérapie

Nibeye Y, Tadjoro F, Atenguena E, Ndom P

PDF (Français (Canada))

DOI: https://doi.org/10.5281/hsd.v26i5.6637

Epidemioclinical and Anatomopathological Features of Malignancies of the Upper Aerodigestive Tract at the Hôpital Militaire de Région Numéro 2
Aspects Épidémiocliniques et Anatomopathologiques des Cancers des Voies Aérodigestives Supérieures à l’Hôpital Militaire de Région Numéro 2

Badang AFD, Minka NE, Mouangue-Mbonjo L, Kafand NCVL, Njock LR, Njifou NA

PDF (Français (Canada))

DOI: https://doi.org/10.5281/hsd.v26i5.6638

Catastrophisation, Emotional Distress and the Experience of Pain in a Cancer Patient Population
Catastrophisation, Détresse Émotionnelle et Expérience de la Douleur au Sein d’une Population de Patients Souffrant de Cancer

Epopa EDD, Njiengwe E, Eyoum C, Engbang NJ-P

DOI: https://doi.org/10.5281/hsd.v26i5.6639

High Level of Hepatitis Delta Virus Replication in Patients Co-Infected with Hepatitis Delta Virus and Hepatitis B Virus at the Centre Pasteur of Cameroon
Haut Niveau de Réplication du Virus de l’Hépatite Delta chez les Patients Co-Infectés par le Virus de l’Hépatite Delta et le Virus de l’Hépatite B au Centre Pasteur du Cameroun

Mbouyap PR, Ngono L, Noumsi T, Lissock F, Zekeng M, Epote A, Belinga S, Njouom R

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DOI: https://doi.org/10.5281/hsd.v26i5.6640

Performance of Serological Tests during Screening for Four Blood-borne Infections in Voluntary Blood Donors in Yaoundé, Cameroon
Performance des Tests Sérologiques au Cours du Dépistage de Quatre Infections Transmissibles par la Voie Sanguine chez les Donneurs Bénévoles de Sang à Yaoundé, Cameroun

Angandji P, Ewodo T, Ateba G, Tayou C

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DOI: https://doi.org/10.5281/hsd.v26i5.6641

Contribution of the Computerized Laboratory System to the Reduction of Non-Conformities
Apport du Système Informatisé de Laboratoire dans la Réduction des Non-Conformités

Mbouna SFM, Ngogang M-P, Voundi-Voundi E, Messanga-Zindi J, Edinga BE, Ama Moor VJ, Fokunang C

PDF (Français (Canada))

DOI: https://doi.org/10.5281/hsd.v26i5.6644

Reference Intervals for Serum Uric Acid in Sub-Saharan African Adults: Case of Cameroon
Intervalles de Référence de l'Acide Urique Sérique chez les Adultes d'Afrique Subsaharienne : Cas du Cameroun

Mbouna SFM, Nkeck JR, Edinga BD, Neri-Atabe N, Tang M, Tang DC, Ama-Moor VJ

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Evaluation of Functional Capacity by the Six-Minute Walk Test of Post-Heart Surgery Patients: A Cross-Sectional Study at the Yaoundé General Hospital
Évaluation de la Capacité Fonctionnelle par le Test de Marche de Six Minutes des Patients en Post-Chirurgie Cardiaque : Étude Transversale à l’Hôpital Général de Yaoundé

Tsague KHN, Ngo-Yon LC, Nsangou PN, Siddikatou D, Ndobo V, Mve MC, Kobe ZF, Dakleu DM, Lowe KS, Tsafack SGC, Tchuimkam S, Menoue C, Boombhi J, Menanga AP

DOI: https://doi.org/10.5281/hsd.v26i5.6646

Management of Lower Limb Bone Loss Using the Masquelet Technique
Prise en Charge des Pertes de Substances Osseuses du Membre Inférieur par la Technique de Masquelet

Esseme Ndjie Camille Harold, Sawadogo Rachel, Darga Christian, Sawadogo Mamoudou

PDF (Français (Canada))

DOI: https://doi.org/10.5281/hsd.v26i5.6647

High Prevalence and Risk Factors of Periodontitis among Blood Donors in a Sub-Saharan Population
Prévalence Élevée et Facteurs de Risque de la Parodontite chez les Donneurs de Sang d'une Population Subsaharienne

Angandji P, Mbuy C, Ndoumba A, Mbanya D

PDF

DOI: https://doi.org/10.5281/hsd.v26i5.6650

State of Thoracic Trauma in Sub-Saharan Africa: A Study of 358 Cases in Yaoundé
État des Lieux des Traumatismes du Thorax en Afrique Sub-Saharienne : Étude de 358 Cas à Yaoundé

Mbouna SFM, Bang GA, Guiffo MLR, Bwelle GM, Bang N, Bitang-A-Mafok L, Ngo-Nonga B, Essomba

PDF (Français (Canada))

DOI: https://doi.org/10.5281/hsd.v26i5.6651

Infectious Transfusion Safety During the COVID-19 Pandemic: Evaluation of Selected Serological Markers at the Centre Hospitalier et Universitaire de Yaoundé, Cameroon
Sécurité Transfusionnelle Infectieuse Pendant la Pandémie à COVID-19 : Évaluation de Quelques Marqueurs Sérologiques au Centre Hospitalier et Universitaire de Yaoundé, Cameroun

Esther Voundi Voundi, Annick Ndoumba Mintya, Rodrigue Bouopda, Claude Tayou Tagny, Dora Mbanya

PDF (Français (Canada))

Comparison of Salivary Parameters in COVID-19 Positive Vs COVID-19 Negative Individuals During a Mass Campaign: A Case-Control Study
Comparaison des Paramètres Salivaires chez les Individus COVID-19 Positifs et COVID-19 Négatifs lors d'une Campagne de Masse : Une Étude Cas-Témoins

Esther Voundi-Voundi, Marie Gaël Ngono, Marie Elvire Nokam Abena, Jacqueline Michele Lowe, Christiane Medi-Sike, Marie Paule Ngogang, Constant Anatole Pieme

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DOI: https://doi.org/10.5281/hsd.v26i5.6653

The Book of Abstracts
Le Livre des Résumés

Ngo Um Esther

Please, Download the Instructions to Authors Here, and Read Carefully Before Submitting

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DOI: https://doi.org/10.5281/hsd.v26i5.6679

Please, Download the Whole Issue Here

Samuel Nko'o Amvene

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DOI: https://doi.org/10.5281/hsd.v26i5.6680

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Dean, FMBS/UYI

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Pr Alfred K. Njamnshi

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Pr Marie José Essi

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Pr Oudou Njoya

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Scope - Editorial Policies

AIMS AND SCOPE
Health Sciences and Disease, is an open source, peer reviewed medical journal that covers all aspects of medicine, pharmacy, biomedical and health sciences, including public health and societal issues. It is an “online first” publication, which means that all the publications articles appear on the website before being included in the print journal. The papers are published in full on the website, with open access. Our vision is to be the leader medical journal in our region. Our mission is to inform and educate all the health professionals and to promote constructive debate on health issues that matter in the management not only of diseases but of health as a whole.
Health Sciences and Disease is the official publication of the Faculty of Medicine and Biomedical Sciences of the University of Yaoundé I. Its team is based in Yaounde (Cameroon).
Acceptance of manuscripts is based on the originality, the quality of the work and validity of the evidence, the clarity of presentation, and the relevance to our readership. Publications are expected to be concise, well organized and clearly written. Authors submit a manuscript with the understanding that the manuscript (or its essential substance) has not been published other than as an abstract in any language or format and is not currently submitted elsewhere for print or electronic publication.

JOURNAL FACTS
Publisher
Faculty of Medicine and Biomedical Sciences, The University of Yaounde I.

Indexing
HSD is indexed by Google Scholar, DOAJ, ROAD, JournalTOCs, African Index Medicus (WHO).
As an institutional publication of the Faculty of Medicine and Biomedical Sciences of the University of Yaounde I, Health Sciences and Disease is accredited by the Conseil Africain et Malgache pour l’Enseignement Supérieur (CAMES) (N° 220)

Health Sciences and Disease home page: http://hsd-fmsb.org

Contact information
hsdeditor3@gmail.com. / nkooamvenes@gmail.com
Health Sciences and Disease
Faculty of Medicine and Biomedical Sciences
PO Box 1364, Yaoundé Cameroon.

ISSN (print): 1684-2782 / EISSN (online) : 2309-6535

MANUSCRIPT SUBMISSIONS
The preferred way for submission is the online submission. Please, refer to the instructions to authors and to the Health Sciences and Disease home page: http://hsd-fmsb.org. Otherwise, manuscripts can be addressed to nkooamvenes@gmail.com.

LANGUAGES OF SUBMISSIONS
English, French

EDITORIAL POLICIES
Ethics
HSD’s Policy Committee follows the recommendations of the International Committee of Medical Journal Editors (ICMJE), the World Association of Medical Editors (WAME), and the Committee on Publication Ethics (COPE) for guidance on policies and procedures related to publication ethics. The policies for HRA have been adapted from those three advisory bodies and, where necessary, modified and tailored to meet the specific content, audiences, and aims of HSD.
Peer review process
Research manuscripts are initially checked by the editor in chief or section editor for identification of gross deficiencies. At this stage, the proposal may be rejected. After this initial screening, articles are sent to one or two-reviewers whose names are hidden from the author and whose review is guided by a checklist (single anonymized review). The review summary is signed by the reviewer and is not posted with article. The review process may take days to weeks to reach a final decision that is the responsibility of the editor in chief. The duration from submission to publication may take one to six months (average: 6 months). So, the authors should avoid contacting the editorial office less than 6 weeks after the initial submission.
Plagiarism, scientific misconduct
Manuscripts are randomly checked for plagiarism with available free tools. Those proven of plagiarism are returned to the authors without peer review. The editors reserve the right to request that the authors provide additional data collected during their investigations. The editors also reserve the right to send a copy of the manuscript and data in question to the author’s dean, university, or supervisor or, in the case of an investigation being funded by an agency, to that funding agency for appreciation.
Conflict of interest
At the time of submission, authors are asked to disclose whether they have any financial interests or connections, direct or indirect, or other situations that may influence directly or indirectly the work submitted for consideration.
Human and animal studies
Manuscripts reporting results of prospective or retrospective studies involving human subjects must document that appropriate institutional review board (IRB) approval and informed consent were obtained (or waived by the IRB) after the nature of the procedure(s) had been fully explained. In any case, medical research involving human subjects should comply with the Declaration of Helsinki (2013).
Authorship
To be listed as an author, an individual must have made substantial contributions to all three categories established by the ICMJE (http://www.icmje.org): (a) “conception and design, or acquisition of data, or analysis and interpretation of data,” (b) “drafting the article or revising it critically for important intellectual content,” and (c) “final approval of the version to be published.” Individuals who have not made substantial contributions in all three categories but who have made substantial contributions either to some of them or in other areas should be listed in acknowledgments.
Please limit the number of authors to ten when this is feasible.
Content licensing - Open access compliance
Since 2013 , articles published in HSD are Open Access and distributed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0), which means that all content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher, provided the original work is properly cited.
Artificial Intelligence (AI)–Assisted Technology
At submission, the authors should disclose whether they used artiﬁcial intelligence (AI)–assisted technologies in the production of the publication and how AI was used. However, authors should not list AI and AI-assisted technologies as an author or co-author, nor cite AI as an author.
ARTICLE PROCESSING CHARGES (APC)
Article submission is free of charges, but if your paper is accepted for publication, you will be asked to pay article processing charges to cover publications costs, depending on the type, complexity and length of the work, and on the number of authors
FAST TRACK
Inquiries about fast track, manuscript status and preparation, as well as letters to the editor, should be directed to:
Nko’o Amvene Samuel
Editor-in-Chief, Health Sciences and Disease
Email: nkooamvenes@gmail.com

COPYRIGHT NOTICE
Authors who publish with this journal agree to the following terms:
• Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
• Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
• Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.

Journal Description

Current Issue

Cover Page

Please, Download the Front Cover Page Here

In This Issue

Please, Download the Full Contents Page Here

Abstracts 3rd Scientific Days FMBS

The Dean's Adress
Le Mot du Doyen

Scientific programme at a glance

Arrimage Moléculaire des Triterpènes Isolés de l'Écorce de Vernonia Conferta sur le Cancer de la Peau Médié par les Protéines MRCK Alpha et Bêta
Molecular Docking of Triterpenes Isolated from the Bark of Vernonia conferta on Skin Cancer Mediated by MRCK Alpha and Beta Proteins

Anticancer Potential of Some Plants from the Cameroon Pharmacopoeia
Potentiel Anticancéreux de Quelques Plantes de la Pharmacopée Camerounaise

Formulation of a syrup based on Eucalyptus leaves
Formulation d’un Sirop à Base de Feuilles d’Eucalyptus

Study of a Diet Drink based on Solanum Sp. fruit
Étude d’une Boisson Diététique à Base de Fruits de Solanum Sp

Operated Digestive Cancers in Cameroon: Typology and Diagnostic Staging
Cancers Digestifs Opérés au Cameroun : Typologie et Stadification au Diagnostic

Indications and Results of Colonoscopies in Subjects Aged 60 and Over in Yaoundé, (Cameroon)
Indications et Résultats des Coloscopies chez les Sujets Âgés de 60 ans et Plus à Yaoundé (Cameroun)

Molecular Classification of Breast Cancers Diagnosed at the Centre Pasteur in Cameroon
Classification Moléculaire des Cancers du Sein Diagnostiqués au Centre Pasteur du Cameroun

Cytopathological Aspects of the Uterine Cervix of Pregnant Women in Yaoundé
Aspects Cytopathologiques du Col Utérin chez la Femme Enceinte à Yaoundé

Prevalence of High-Risk Human Papillomavirus Serotypes and Confrontation with Available Vaccine Antigens: The Case of Cameroon
Prévalence des Sérotypes de Papillomavirus Humain à Haut Risque et Confrontation avec les Antigènes Vaccinaux Disponibles : Le Cas du Cameroun

Impact of Oral Cryotherapy on the Occurrence of Oral Mucositis in Cancer Patients Treated with Chemotherapy
Impact de la Cryothérapie Orale sur la Survenue de la Mucite Buccale chez les Patients Cancéreux Traités par Chimiothérapie

Epidemioclinical and Anatomopathological Features of Malignancies of the Upper Aerodigestive Tract at the Hôpital Militaire de Région Numéro 2
Aspects Épidémiocliniques et Anatomopathologiques des Cancers des Voies Aérodigestives Supérieures à l’Hôpital Militaire de Région Numéro 2

Catastrophisation, Emotional Distress and the Experience of Pain in a Cancer Patient Population
Catastrophisation, Détresse Émotionnelle et Expérience de la Douleur au Sein d’une Population de Patients Souffrant de Cancer

Contribution of the Computerized Laboratory System to the Reduction of Non-Conformities
Apport du Système Informatisé de Laboratoire dans la Réduction des Non-Conformités

Reference Intervals for Serum Uric Acid in Sub-Saharan African Adults: Case of Cameroon
Intervalles de Référence de l'Acide Urique Sérique chez les Adultes d'Afrique Subsaharienne : Cas du Cameroun

Management of Lower Limb Bone Loss Using the Masquelet Technique
Prise en Charge des Pertes de Substances Osseuses du Membre Inférieur par la Technique de Masquelet

High Prevalence and Risk Factors of Periodontitis among Blood Donors in a Sub-Saharan Population
Prévalence Élevée et Facteurs de Risque de la Parodontite chez les Donneurs de Sang d'une Population Subsaharienne

State of Thoracic Trauma in Sub-Saharan Africa: A Study of 358 Cases in Yaoundé
État des Lieux des Traumatismes du Thorax en Afrique Sub-Saharienne : Étude de 358 Cas à Yaoundé

Comparison of Salivary Parameters in COVID-19 Positive Vs COVID-19 Negative Individuals During a Mass Campaign: A Case-Control Study
Comparaison des Paramètres Salivaires chez les Individus COVID-19 Positifs et COVID-19 Négatifs lors d'une Campagne de Masse : Une Étude Cas-Témoins

The Book of Abstracts
Le Livre des Résumés

Instructions to authors

Please, Download the Instructions to Authors Here, and Read Carefully Before Submitting

Whole Issue

Please, Download the Whole Issue Here