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Abstract
Objectifs. Décrire les aspects épidémiologiques, diagnostiques et thérapeutiques des tumeurs de vessie 0 Mopti. Patients et méthodes. Il s’agissait d’une étude transversale rétrospective, descriptive portant sur les cas de tumeurs de vessie reçus à l’hôpital Sominé DOLO de Mopti entre le 1er Janvier 2012 et le 30 Novembre 2016. Résultats. 117 cas de tumeur de vessie ont été diagnostiqués. L’incidence annuelle était de 23,4 cas. L’âge moyen était de 49,79 ans avec une prédominance masculine à 1,72. Le motif de consultation a été dominé par les troubles de la miction, 34,19% (n= 40) et l’hématurie, 29,92% (n= 35). L’échographie vésico-prostatique, 82,90% (n= 97) des cas, la cystoscopie, 56,41% des cas (n= 66), ont généralement permis de poser le diagnostic. Le bilan d’extension a retrouvé une atteinte ganglionnaire dans 76,07% (n= 89) des cas, des métastases à distance dans 25,63% (n= 30) des cas. Les traitements effectués ont été la résection trans-urétrale de la vessie, 36,76% (n= 43), les dérivations urinaires externes, 36,76% (n= 43), la chirurgie d’exérèse partielle ou totale, 16,22% (n = 19), une abstention chirurgicale, 10,26% (n=12) des cas. Les suites opératoires ont été simples dans 81,91% (n= 86) des cas. Le carcinome épidermoïde, 82,14%, était l’histologie majoritaire. La survie globale à un an a été de 63,24% (n= 74). Conclusion. À Mopti, les tumeurs de vessie sont presque toutes diagnostiquées à un stade avancé. Le traitement est le plus souvent palliatif.
ABSTRACT
Objective. To describe the epidemiological, diagnostic and therapeutic aspects of bladder tumors. Patients and methods. This was a transversal retrospective, descriptive study of bladder tumor cases received between January 1, 2012 and November 30, 2016 in Sominé DOLO hospital. Results. 117 cases of bladder tumor were diagnosed. The annual incidence was 23.4 cases. The mean age was 49, 79 years with a male predominance at 1.72. The reason for consultation was dominated by micturition trouble, 34, 19% (n= 40) and hematuria, 29, 92% (n= 35). Vesico-prostatic ultrasound, 82.90% (n= 97) and cystoscopy, 56.41% (n= 66), generally found the diagnosis. The extension assessment found lymphadenopathy in 76, 07 (n=89), distant metastases in 25, 63 (n=19) of cases. The treatments performed were TURB (trans urethral resection of bladder), 36, 76% (n=43), external urinary diversions, 36, 76% (n=43), partial or total excision surgery, 16, 22% (n=19), surgical abstention, 10, 22% (n=12) of cases. Operative follo-up was simple in 81, 96% (n=86) of cases. Squamous cell carcinoma, 82, 14% was the majority histology. 1-year overall survival was 63.24%. Conclusion. Bladder tumors were almost all diagnosed at an advanced stage, the treatment was most often palliative.
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References
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References
American Cancer Society. Cancer Facts & Figures 2016. Atlanta: American
Cancer Society; 2016.
Ferlay J, Soerjomataram I, Ervik M, Dikshit R, Eser S, Mathers C, Rebelo M,
Parkin DM, Forman D, Bray, F. GLOBOCAN 2012 v1.0, Cancer Incidence and
Mortality Worldwide: IARC Cancer Base No. 11 . Lyon, France: International Agency for Research on Cancer. 2013. http://globocan.iarc.fr. Accessed 25 Feb 2016.
World Cancer Report 2014. In: Stewart BW, Wild CP, editors. Lyon, France:
International Agency for Research on Cancer; 2014. p 444–52.
Benhamou S., Bonastre J.,Groussard K., Radvanyi F., Allory Y., Lebret T. A
prospective multicenter study on bladder cancer: the COBLAnCE cohort. BMC Cancer (2016) 16:837 DOI 10.1186/s12885-016-2877-x.
Pons F, Orsola A, Morote J, Bellmunt J. Variant forms of bladder cancer: basic
considerations on treatment approaches. Curr Oncol Rep. 2011;13:216-21.
Chalasani V, Chin JL, Izawa JI. Histologic variants of urothelial bladder cancer
and nonurothelial histology in bladder cancer. Can Urol Assoc J. 2009;3:S193- 98.
IARC (1994) Monographs on the Evaluation of Carcinogenic Risks to Humans
Volume 61 Schistosomes, Liver Flukes and Helicobacter pylori. 279 p.
IARC (2012) Monographs on the Evaluation of Carcinogenic Risks to Humans.
Biological Agents. Volume 100B A review of human carcinogens. 499 p.
Salem S, Mitchell RE, El-Alim El-Dorey A, et al. Successful control of
Schistosomiasis and the changing epidemiology of bladder cancer in Egypt. BJU Int 107(2):206–11.
TRAORE MT, JALLOH M, YEVI M, NDOYE M, LABOU I, NIAN G L, GUEYE
SM. La resection trans-urétrales des tumeurs de vessie à l’hôpital general de Grand Yoff à propos de 141 cas. Uro Andro Volume 1 N° Juillet 201810 ; 463-67.
Lougue-Sorgho L.C., Cisse R., Kagone M., Bamouni Y.A. , Tapsoba T.L.
Sanou A. Radiographie et échographie dans la prise en charge des tumeurs de la vessie : à propos de 71 cas au Centre hospitalier national Yalgado Ouedraogo (Burkina Faso ). Bull Soc Pathol Exot, 2002, 95, 4, 244-47.
Diao B., Amath T., Fall B., Fall P.A., Diémé M.J., Steevy N.N., Ndoye A.K., Ba M.,
Mendès V., Diagne B.A.. Les cancers de vessie au Sénégal : particularités épidémiologiques, cliniques et histologiques. Prog Urol 2008;18:445-48.
Moschini M, et al., The surgical management of patients with clinical stage T4
bladder cancer: A single institution experience. Eur J Surg Oncol (2016), http://dx.doi.org/10.1016/j.ejso.2016.08.024.
McCombie S. P., Bangash H.K., Kuan M., Thyer I., Lee F.,Hayne D. Delays in
the diagnosis and initial treatment of bladder cancer in Western Australia.
BJU International 2017 doi:10.1111/bju.13939.
Bochner BH, Kattan MW, Vora KC: Postoperative nomogram predicting risk of
Recurrence after radical cystectomy for bladder cancer. J Clin Oncol 24 2006:3967-72.
Galsky M.D., Stensland K., Sfakianos J.P., Mehrazin R., Diefenbach M.,
Mohamed N., Tsao C.K., Boffetta P., Wiklund P, William K. Oh, Mazumdar M., Ferket B. Comparative Effectiveness of Treatment Strategies for Bladder Cancer with Clinical Evidence of Regional Lymph Node Involvement. Journal of clinical oncology 34 N°22 Août 2016; 2627- 35.
SAKKAS J.L. Clinical pattern and treatment of squamous cell carcinoma
of the bladder. Int. Surg., 1966, 45, 71-76.
RUNDLE J.S.H., HART A.J.L., MCGEORGE A., SMITH J.S., MALCOLM A.J.,
SMITH P.M. Squamous cell carcinoma of bladder. A review of 114 patients. Br. J. Urol., 1982, 54, 522-26.
JOHNSON D.E., SCHOENWALD M.B., AYALA A.G., MILLER L.S. Squamous
cell carcinoma of the bladder. J. Urol., 1976, 115,542-44.
RICHIE J.P., WAISMAN J., SKINNER D.G., DRETLER S.P. Squamous cell
carcinoma of the bladder : treatment by radical cystectomy. J. Urol., 1976, 115, 670-72.
PREMPREE T., AMORNMARN R. Radiation management of squamous cell
carcinoma of the bladder. Acta Radiol. Oncol., 1984, 23,37-42.