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Abstract

Introduction. Abnormal blood sugar level (dysglycemia) on admission in severely ill children is metabolic response to acute stress. This is not found in all patients and we hypothesized that in non-diabetic children, abnormal glycaemic profile on admission worsened patient’s evolution in hospital. Materials and methods. We carried out a prospective cohort study in a paediatric emergency unit during 6 months. We included children with a severe acute medical condition, aged between 28 days and 16 years. Blood sugar level was tested in each patient on admission. The data on final diagnosis, evolution were collected. We compared data of children with or without dysglycemia on admission. Pearson’s chi square test and Fisher’s exact test were used to compare categorical variables while Kruskal-Wallis test and Mann Whitney U were used to compare numerical variables. Results. We included 203 children with median age 30 months (IQR: 14-68 months). The prevalence of hypoglycemia on admission was 3.45% and stress hyperglycemia on admission 31.53%. Unconsciousness and respiratory distress were the most frequent symptoms significantly associated with dysglycemia (P<0.05). Children with dysglycemia were 7.1 times more likely to be transferred to the intensive care unit and 7.4 times more likely to die compared to those with a normal glycemia (p<0.01). Conclusion. Dysglycemia occurs in 34.9% of patients admitted in our paediatric emergency unit and was associated with higher risk of mortality.

Keywords

Hypoglycemia, hyperglycemia, in-hospital mortality

Article Details

How to Cite
Suzanne Sap Ngo Um, Isabelle Mekone, Kenneth Nabengu Okenye, Helène Kamo, Jocelyn Tony Mbono Ritha, Claude Kalla, & Paul Olivier Koki. (2022). Should Stress Hyperglycemia be Considered as Severity Criteria for Malaria and Sepsis in Children?. HEALTH SCIENCES AND DISEASE, 23(7). Retrieved from https://hsd-fmsb.org/index.php/hsd/article/view/3777

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