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PDF Table 1: HIV seroprevalence rate according to health units, sex and pregnant women among people attending outpatient clinics in Lebialem Division Table 2: The number of samples tested and percentage reactive samples among people attending outpatient clinics in Lebialem Division, according to age groupings Table 3: Occupational prevalence of HIV among people attending outpatient clinics in Lebialem Division

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Abstract

 Identifying an appropriate population for HIV Vaccine clinical trials is currently a major challenge to HIV vaccine clinical site preparedness. A cross sectional hospital-based HIV prevalence survey was carried out in four clinics in Lebialem Division, to ascertain the suitability of this population for HIV vaccine trials.  A questionnaire was administered to 1037 participants (age >15), and 5 ml of blood collected, sera separated and screened against HIV-1 and HIV-2 using a parallel testing algorithm with Determine and STAP-PAK as main  test  kits and Oraquick as tie-breaker.

The prevalence of HIV varied in the four clinics with Lewoh health unit having the highest HIV prevalence (13.8%), followed by Mary Health of Africa (11.2%), Menji (8.4%) and lastly Azi (3.0). HIV prevalence among women in general was 11.4%, while men and pregnant women had 10.2% and 5% respectively.  Of the 108 sero-positive samples, 34 (31%) were from the 18-27 and 36 (33.3%) from the 28-37 age groups.  It decreased with increase in age as only 2 samples were positive for those who were > 68 years old. There was a significant difference in HIV prevalence by occupation. The prevalence was significantly higher (P<0.001) among traders (48.60%), and civil servants (22.82%) compared with the farming population (4.30%), and students (8.60%).

Though the HIV prevalence in Lebialem Division is high, making it a suitable population to explore for developing cohorts for vaccine trials, further studies that should look at HIV incidence among this population are recommendation.

Keywords

HIV Seroprevalence rural area Cameroon.

Article Details

How to Cite
Njukeng, A., Nwobegahay, J., & Nwobah, N. S. (2013). DEVELOPING COHORTS FOR HIV VACCINE TRIALS IN A RURAL AREA OF CAMEROON: CASE STUDY OF LEBIALEM DIVISION. HEALTH SCIENCES AND DISEASE, 13(1). https://doi.org/10.5281/hsd.v13i1.72
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