Crohn’s Disease in a Developing African Mission Hospital: a Rare Case Report

Alegbeleye Josep Bamidele Johnson

Abstract


ABSTRACT
The chronic and lifelong gastrointestinal tract disorder of Crohn’s Disease (CD) is a type of inflammatory bowel disease with unclear causative agent. CD is directly correlated with a triad group of predisposing factors including genetic problems, immune system malfunctions and environmental factors. Though it is uncommon in Africa yet we come across this entity sparingly. The signs and symptoms of CD overlap with many other abdominal disorders like tuberculosis, ulcerative colitis, irritable bowel syndrome etc. It may even involve systems other than GIT.Although it is difficult to make an accurate diagnosis of this disease, many diagnostic armamentaria are available to suggest its presence. Most of the patients are treated conservatively yet a few may require surgical intervention especially presenting with complications like intestinal obstruction, perforations, abscess and fistula formations.We have encountered one such case of intestinal obstruction requiring surgical intervention which was confirmed to be CD histopathologically. Rarity and clinical curiosity of this entity suggest reporting of this case.
RÉSUMÉ
Le trouble de l’appareil gastro-intestinal chronique et persistant de la maladie de Crohn (MC) est un type de maladie inflammatoire de l’intestin sans cause évidente. La MC est directement corrélée à une triade de facteurs prédisposants, notamment des problèmes génétiques, des dysfonctionnements du système immunitaire et des facteurs environnementaux. Les signes et les symptômes de la MC se chevauchent avec de nombreux autres troubles abdominaux tels que la tuberculose, la colite ulcéreuse, le syndrome du côlon irritable, etc. Ils peuvent même concerner des systèmes autres que le système digestif. Bien qu’il soit difficile de poser un diagnostic précis de cette maladie, de nombreux signes peuvent la suggérer. La plupart des patients sont traités de façon conservatrice, mais quelques-uns peuvent nécessiter une intervention chirurgicale, en particulier lors des complications telles qu'une obstruction intestinale, des perforations, un abcès et des fistules. Nous avons rencontré un cas d'obstruction intestinale nécessitant une intervention chirurgicale confirmée histopathologiquement comme une MC. La rareté et la curiosité clinique de cette entité suggèrent de signaler ce cas.


Keywords


Crohn’s disease; Autoimmune disorder; Granulomatous colitis; Regional enteritis

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