Main Article Content
Abstract
RÉSUMÉ
Introduction. Depuis fin Décembre 2019, le monde fait face à une crise sanitaire, celle du COVID-19. Nous avons voulu décrire les aspects tomodensitométriques (TDM) thoracique du COVID-19 chez les patients de plus de 65 ans à l’hôpital général de référence de Niamey. Méthodologie. Nous avons mené une étude prospective de 3 mois chez les patients de plus de 65 ans, positifs au COVID-19 et ayant bénéficié d’un scanner thoracique avec ou sans produit de contraste. Résultats. Notre étude a concerné 21 patients. L’âge moyen était 70,76 ans allant de 66 et 103 ans, avec une prédominance masculine (85,71%). Toutes les TDM étaient sans injection de produit de contraste. L’hyperdensité en verre dépoli a été retrouvée dans 57 % des cas, l’aspect en crazy-paving dans 19 % des cas et la condensation pulmonaire dans 76 % des cas. La topographie mixte était prédominante (57%), elle était sous-pleurale dans 33% des cas. L’atteinte était multi lobaire et prédominante au lobe inférieur dans 81% des cas ; les lésions pulmonaires étaient bilatérales dans 95 % ; l’atteinte était sévère dans 19% des cas et critique dans 14% des cas ; une pleurésie était observée chez 3 des patients. Conclusion. Les aspects TDM des atteintes thoraciques de la COVID-19 sont polymorphes avec une bonne sensibilité et peuvent servir d’alternative pour diagnostiquer les patients positifs à l’infection.
ABSTRACT
Introduction. Since end of December 2019, the world is facing a health crisis, the COVID-19. We aimed to describe the thoracic computed tomography (CT) aspects of COVID-19 in patients over 65 years of age at the general referral hospital of Niamey. Methodology. We conducted a prospective study over 3-month in patients over 65 years of age, positive for COVID-19 and who had undergone a thoracic CT scan with or without contrast medium. Results. Our study involved 21 patients. The mean age was 70.76 years ranging from 66 to 103 years, with a male predominance (85.71%). All chest CT scans were done without contrast injection. Hyperdense ground glass was found in 57% of cases, crazy-paving in 19% and lung condensation in 76%. Mixed topography was predominant (57%), subpleural in 33% of cases. Involvement was multi-lobar and predominantly in the lower lobe in 81% of cases; lung lesions were bilateral in 95%; involvement was severe in 19% of cases and critical in 14%; pleurisy was observed in 3 of the patients. Conclusion. Signs of COVID-19 on chest CT scan are polymorphic with good sensitivity and can be used as alternative to diagnose COVID-19.
Keywords
Article Details

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
References
- Gao GF. From “A” IV to “Z” IKV: attacks from emerging and re-emerging pathogens. Cell 2018; 172:1157-1159.
- Weiss SR, Leibowitz JL. Coronavirus pathogenesis. Adv Virus Res 2011; 81:85-164.
- Masters PS, Perlman S. Coronaviridae. In: Knipe DM, Howley PM, eds. Fields virology. 6th ed. Lippincott Williams & Wilkins, a Wolters Kluwer business, Philadelphia 2013. Vol 2, p.825.
- Su S, Wong G, Shi W, et al. Epidemiology, genetic recombination, and pathogenesis of coronaviruses. Trends Microbiol 2016; 24:490-502.
- Cui J, Li F, Shi ZL. Origin and evolution of pathogenic coronaviruses. Nat Rev Microbiol 2019 ;17 :181-192.
- Zhong NS, Zheng BJ, Li YM, et al. Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong, People’s Republic of China, in February, 2003. Lancet 2003; 362:1353-1358.
- Ksiazek TG, Erdman D, Goldsmith CS, et al. A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med 2003; 348:1953-1966.
- Drosten C, Günther S, Preiser W, et al. Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med 2003; 348:1967-1976.
- Zaki AM, van Boheemen S, Bestebroer TM, Osterhaus AD, Fouchier RA. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med 2012; 367:1814-1820.
- Lu R, Zhao X, Li J, et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet 2020; 395:565-574.
- Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med 2020; 382:727-733.
- World Health Organization. Coronavirus disease (COVID-19) outbreak (https://www.who.int).
- Xie X, Zhong Z, Zhao W, Zheng C, Wang F, Liu J. Chest CT for Typical 2019-nCoV Pneumonia: Relationship to Negative RT-PCR Testing. Radiology. 2020 Feb 12:200343.
- Ai T, Yang Z, Hou H, et al. Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases. Radiology. 2020 Feb 26:200642.
- .Chen, TieLong, Zhe Dai, Pingzheng Mo, et al. « Clinical characteristics and outcomes of older patients with coronavirus disease 2019 (COVID-19) in Wuhan, China (2019): a single-centered, retrospective study ». The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 11 avril 2020, glaa089. https://doi.org/10.1093/gerona/glaa089.
- .Plaçais, L., et Q. Richier. « COVID-19 : caractéristiques cliniques, biologiques et radiologiques chez l’adulte, la femme enceinte et l’enfant. Une mise au point au cœur de la pandémie ». La Revue De Medecine Interne 41, no 5 (mai 2020): 308 18. https://doi.org/10.1016/j.revmed.2020.04.004.
- .Pontone, Gianluca, Stefano Scafuri, Maria Elisabetta Mancini, et al. « Role of computed tomography in COVID-19 ». Journal of Cardiovascular Computed Tomography, 4 septembre 2020. https://doi.org/10.1016/j.jcct.2020.08.013.
- . UFUK, Furkan, et Recep SAVAŞ. « Chest CT features of the novel coronavirus disease (COVID-19) ». Turkish Journal of Medical Sciences 50, no 4 (23 juin 2020): 664-78. https://doi.org/10.3906/sag-2004-331.
- .K. Li, J. Wu, F. Wu, et al.The clinical and chest CT features associated with severe and critical COVID-19 pneumonia Invest Radiol (2020), p. 10, 10.1097/RLI.000000000000067204.
- . H. Shi, X. Han, N. Jiang, et al. Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China : a descriptive study Lancet Infect Dis, 20 (4) (2020), pp. 425-434
- . Carotti, Marina, Fausto Salaffi, Piercarlo Sarzi-Puttini, et al. « Chest CT features of coronavirus disease 2019 (COVID-19) pneumonia: key points for radiologists ». La Radiologia Medica, 4 juin 2020, 1-11. https://doi.org/10.1007/s11547-020-01237-4.
- . Tabatabaei, Seyed Mohammad Hossein, Hamidreza Talari, Fahimeh Moghaddas, et Hamid Rajebi. « Computed Tomographic Features and Short-term Prognosis of Coronavirus Disease 2019 (COVID-19) Pneumonia: A Single-Center Study from Kashan, Iran ». Radiology: Cardiothoracic Imaging 2, no 2 (1 avril 2020): e200130. https://doi.org/10.1148/ryct.2020200130.
- . Salehi, Sana, Aidin Abedi, Sudheer Balakrishnan, et Ali Gholamrezanezhad. « Coronavirus Disease 2019 (COVID-19): A Systematic Review of Imaging Findings in 919 Patients ». American Journal of Roentgenology 215, no 1 (14 mars 2020): 87-93. https://doi.org/10.2214/AJR.20.23034.
- . Ketfi, Abdelbassat, Omar Chabati, Samia Chemali, et al. « Profil clinique, biologique et radiologique des patients Algériens hospitalisés pour COVID-19 : données préliminaires ». The Pan African Medical Journal 35, no 77 (15 juin 2020). https://doi.org/10.11604/pamj.supp.2020.35.2.23807.
- . Amvene SN, Mbole J, A JM, Amvene MRN, Tapouh JRM, Mbongo’o GC, et al. Le Coronavirus (COVID-19) : Mise au Point pour les Personnels de Santé en Afrique. Health Sci Dis [Internet]. 2 mai 2020 [cité 30 janv 2022];21(5). Disponible sur: https://www.hsd-fmsb.org/index.php/hsd/article/view/2014
References
Gao GF. From “A” IV to “Z” IKV: attacks from emerging and re-emerging pathogens. Cell 2018; 172:1157-1159.
Weiss SR, Leibowitz JL. Coronavirus pathogenesis. Adv Virus Res 2011; 81:85-164.
Masters PS, Perlman S. Coronaviridae. In: Knipe DM, Howley PM, eds. Fields virology. 6th ed. Lippincott Williams & Wilkins, a Wolters Kluwer business, Philadelphia 2013. Vol 2, p.825.
Su S, Wong G, Shi W, et al. Epidemiology, genetic recombination, and pathogenesis of coronaviruses. Trends Microbiol 2016; 24:490-502.
Cui J, Li F, Shi ZL. Origin and evolution of pathogenic coronaviruses. Nat Rev Microbiol 2019 ;17 :181-192.
Zhong NS, Zheng BJ, Li YM, et al. Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong, People’s Republic of China, in February, 2003. Lancet 2003; 362:1353-1358.
Ksiazek TG, Erdman D, Goldsmith CS, et al. A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med 2003; 348:1953-1966.
Drosten C, Günther S, Preiser W, et al. Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med 2003; 348:1967-1976.
Zaki AM, van Boheemen S, Bestebroer TM, Osterhaus AD, Fouchier RA. Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia. N Engl J Med 2012; 367:1814-1820.
Lu R, Zhao X, Li J, et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet 2020; 395:565-574.
Zhu N, Zhang D, Wang W, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med 2020; 382:727-733.
World Health Organization. Coronavirus disease (COVID-19) outbreak (https://www.who.int).
Xie X, Zhong Z, Zhao W, Zheng C, Wang F, Liu J. Chest CT for Typical 2019-nCoV Pneumonia: Relationship to Negative RT-PCR Testing. Radiology. 2020 Feb 12:200343.
Ai T, Yang Z, Hou H, et al. Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases. Radiology. 2020 Feb 26:200642.
.Chen, TieLong, Zhe Dai, Pingzheng Mo, et al. « Clinical characteristics and outcomes of older patients with coronavirus disease 2019 (COVID-19) in Wuhan, China (2019): a single-centered, retrospective study ». The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 11 avril 2020, glaa089. https://doi.org/10.1093/gerona/glaa089.
.Plaçais, L., et Q. Richier. « COVID-19 : caractéristiques cliniques, biologiques et radiologiques chez l’adulte, la femme enceinte et l’enfant. Une mise au point au cœur de la pandémie ». La Revue De Medecine Interne 41, no 5 (mai 2020): 308 18. https://doi.org/10.1016/j.revmed.2020.04.004.
.Pontone, Gianluca, Stefano Scafuri, Maria Elisabetta Mancini, et al. « Role of computed tomography in COVID-19 ». Journal of Cardiovascular Computed Tomography, 4 septembre 2020. https://doi.org/10.1016/j.jcct.2020.08.013.
. UFUK, Furkan, et Recep SAVAŞ. « Chest CT features of the novel coronavirus disease (COVID-19) ». Turkish Journal of Medical Sciences 50, no 4 (23 juin 2020): 664-78. https://doi.org/10.3906/sag-2004-331.
.K. Li, J. Wu, F. Wu, et al.The clinical and chest CT features associated with severe and critical COVID-19 pneumonia Invest Radiol (2020), p. 10, 10.1097/RLI.000000000000067204.
. H. Shi, X. Han, N. Jiang, et al. Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China : a descriptive study Lancet Infect Dis, 20 (4) (2020), pp. 425-434
. Carotti, Marina, Fausto Salaffi, Piercarlo Sarzi-Puttini, et al. « Chest CT features of coronavirus disease 2019 (COVID-19) pneumonia: key points for radiologists ». La Radiologia Medica, 4 juin 2020, 1-11. https://doi.org/10.1007/s11547-020-01237-4.
. Tabatabaei, Seyed Mohammad Hossein, Hamidreza Talari, Fahimeh Moghaddas, et Hamid Rajebi. « Computed Tomographic Features and Short-term Prognosis of Coronavirus Disease 2019 (COVID-19) Pneumonia: A Single-Center Study from Kashan, Iran ». Radiology: Cardiothoracic Imaging 2, no 2 (1 avril 2020): e200130. https://doi.org/10.1148/ryct.2020200130.
. Salehi, Sana, Aidin Abedi, Sudheer Balakrishnan, et Ali Gholamrezanezhad. « Coronavirus Disease 2019 (COVID-19): A Systematic Review of Imaging Findings in 919 Patients ». American Journal of Roentgenology 215, no 1 (14 mars 2020): 87-93. https://doi.org/10.2214/AJR.20.23034.
. Ketfi, Abdelbassat, Omar Chabati, Samia Chemali, et al. « Profil clinique, biologique et radiologique des patients Algériens hospitalisés pour COVID-19 : données préliminaires ». The Pan African Medical Journal 35, no 77 (15 juin 2020). https://doi.org/10.11604/pamj.supp.2020.35.2.23807.
. Amvene SN, Mbole J, A JM, Amvene MRN, Tapouh JRM, Mbongo’o GC, et al. Le Coronavirus (COVID-19) : Mise au Point pour les Personnels de Santé en Afrique. Health Sci Dis [Internet]. 2 mai 2020 [cité 30 janv 2022];21(5). Disponible sur: https://www.hsd-fmsb.org/index.php/hsd/article/view/2014