Main Article Content
Abstract
ABSTRACT
Introduction. Cleft palate are frequently associated with other congenital malformations, particularly cardiac ones, impacting the overall management of patients. There are no data in our setting on the association of cleft palate with congenital heart defects. Methods. We carried out a cross-sectional analytical study with retrospective and prospective data collection during a period of five years, at the Yaounde Gynaeco-Obstetric and Paediatric Hospital. All patients under 18 years of age who consulted for cleft palate were included in our study. Results. We enrolled 76 patients. The median age was 3 months with an interquartile range of [2-6] months. Primary cleft palate was found in 42 patients (55.26%), secondary cleft palate in 4 patients (5.26%) and primary and secondary cleft palate in 30 patients (39.47%). A congenital heart defect was found in 20 of the 76 patients (26.32%). All cardiopathies were simple and non-cyanogenic. The most common was atrial septal defect (17.10%) followed by patent ductus arteriosus (5.26%). There was no significant association between the type of cleft and the type of cardiac anomaly. Conclusion. The prevalence of congenital heart defects in children with cleft palate in Cameroon is high. Cardiac evaluation of these patients is necessary to identify potentially high risk patients.
RÉSUMÉ
Introduction. Les fentes labiopalatines fréquemment associées à d’autres malformations congénitales, notamment celles cardiaques, impactent la prise en charge globale des patients. Il n’existe pas de données dans notre milieu quant à l’association fentes labiopalatines et anomalies cardiaques congénitales. Méthodologie. Nous avons mené une étude transversale analytique à collecte de données rétrospective et prospective sur une période de cinq ans, à l’Hôpital Gynéco-Obstétrique et Pédiatrique de Yaoundé. Etaient inclus dans notre étude, tout patient âgé de moins de 18 ans ayant consulté dans cette formation sanitaire pour fente labiopalatine. Résultats. Nous avons recruté 76 patients. L’âge médian était de 3 mois avec un intervalle interquartile de [2-6] mois. On retrouvait les fentes du palais primaire chez 42 patients (55,26%), les fentes du palais secondaire chez 4 patients (5,26%) et les fentes des palais primaire et secondaire chez 30 patients (39,47%). Une anomalie cardiaque congénitale était retrouvée chez 26,32%. Parmi ces cardiopathies, toutes étaient simples et non cyanogènes. La plus retrouvée était la communication inter auriculaire (17,10%), suivie de la persistance du canal artériel (5.26%). Nous n’avons pas retrouvé d’association significative entre le type de fente et le type d’anomalie cardiaque. Conclusion. La prévalence des anomalies cardiaques congénitales chez les enfants porteurs de fentes labiopalatines au Cameroun est élevée. L’évaluation de ces patients sur le plan cardiaque est nécessaire pour identifier les patients potentiellement à haut risque.
Keywords
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
References
- Global strategies to reduce the health-care burden of craniofacial anomalies : report of WHO Meetings on International Collaborative Research on Craniofacial Anomalies, Geneva, Switzerland, 5-8 November 2000 ; Park City, Utah, U. S. A., 24-26 May 2001 [Internet]. 2022 [cité 20 déc 2022]. Disponible sur: https://apps.who.int/iris/handle/10665/42594
- Sun T, Tian H, Wang C, Yin P, Zhu Y, Chen X, et al. A Survey of Congenital Heart Disease and Other Organic Malformations Associated with Different Types of Orofacial Clefts in Eastern China. PLoS ONE. 21 janv 2013;8(1):e54726.
- Pereira AV, Fradinho N, Carmo S, de Sousa JM, Rasteiro D, Duarte R, et al. Associated Malformations in Children with Orofacial Clefts in Portugal: A 31-Year Study. Plast Reconstr Surg Glob Open. 9 févr 2018;6(2):e1635.
- Altunhan H, Annagür A, Konak M, Ertuğrul S, Ors R, Koç H. The incidence of congenital anomalies associated with cleft palate/cleft lip and palate in neonates in the Konya region, Turkey. Br J Oral Maxillofac Surg. sept 2012;50(6):541‑4.
- Erinoso OA, James O, Sokunbi OJ, Adamson OO, Adekunle AA, Agbogidi OF, et al. Congenital Heart Defects in Orofacial Cleft: A Prospective Cohort Study. Afr J Paediatr Surg AJPS. 2021;18(4):219‑23.
- Beriaghi S, Myers SL, Jensen SA, Kaimal S, Chan CM, Schaefer GB. Cleft lip and palate: association with other congenital malformations. J Clin Pediatr Dent. 2009;33(3):207‑10.
- Rao G, Desai A, Kumar N. Congenital Heart Diseases Associated With Cleft Lip and Palate and Its Impact on Surgical Treatment Planning of Patients With Cleft Lip and Palate-A Cross-Sectional Study. Cleft Palate-Craniofacial J Off Publ Am Cleft Palate-Craniofacial Assoc. févr 2021;58(2):163‑9.
- Akhiwu BI, Efunkoya AA, Akhiwu HO, Adebola RA. Congenital Heart Disease in Cleft Lip and Palate Patients: How Common Is the Association? J Adv Oral Res. SAGE Publications India; 1 mai 2017;8(1‑2):53‑6.
- Barrett WJ, Diedericks BJS, Barrett CL, Joubert G, Turton EW. Congenital heart defects in children with cleft lips and/or palates at an academic hospital in central South Africa. South Afr J Anaesth Analg. Medpharm Publications; avr 2019;25(2):23‑9.
- Panamonta V, Pradubwong S, Panamonta M, Chowchuen B. Prevalence of Congenital Heart Diseases in Patients with Orofacial Clefts: A Systematic Review. J Med Assoc Thail Chotmaihet Thangphaet. août 2015;98 Suppl 7:S22-27.
- Priyadharshini R, James S, Rathinasamy J, R. M, Gopalakrishnan G, Kharlukhi J. A cross-sectional study of cardiac anomalies among children with orofacial cleft - role of echocardiography. Int J Contemp Pediatr. 21 juin 2017;4(4):1274.
References
Global strategies to reduce the health-care burden of craniofacial anomalies : report of WHO Meetings on International Collaborative Research on Craniofacial Anomalies, Geneva, Switzerland, 5-8 November 2000 ; Park City, Utah, U. S. A., 24-26 May 2001 [Internet]. 2022 [cité 20 déc 2022]. Disponible sur: https://apps.who.int/iris/handle/10665/42594
Sun T, Tian H, Wang C, Yin P, Zhu Y, Chen X, et al. A Survey of Congenital Heart Disease and Other Organic Malformations Associated with Different Types of Orofacial Clefts in Eastern China. PLoS ONE. 21 janv 2013;8(1):e54726.
Pereira AV, Fradinho N, Carmo S, de Sousa JM, Rasteiro D, Duarte R, et al. Associated Malformations in Children with Orofacial Clefts in Portugal: A 31-Year Study. Plast Reconstr Surg Glob Open. 9 févr 2018;6(2):e1635.
Altunhan H, Annagür A, Konak M, Ertuğrul S, Ors R, Koç H. The incidence of congenital anomalies associated with cleft palate/cleft lip and palate in neonates in the Konya region, Turkey. Br J Oral Maxillofac Surg. sept 2012;50(6):541‑4.
Erinoso OA, James O, Sokunbi OJ, Adamson OO, Adekunle AA, Agbogidi OF, et al. Congenital Heart Defects in Orofacial Cleft: A Prospective Cohort Study. Afr J Paediatr Surg AJPS. 2021;18(4):219‑23.
Beriaghi S, Myers SL, Jensen SA, Kaimal S, Chan CM, Schaefer GB. Cleft lip and palate: association with other congenital malformations. J Clin Pediatr Dent. 2009;33(3):207‑10.
Rao G, Desai A, Kumar N. Congenital Heart Diseases Associated With Cleft Lip and Palate and Its Impact on Surgical Treatment Planning of Patients With Cleft Lip and Palate-A Cross-Sectional Study. Cleft Palate-Craniofacial J Off Publ Am Cleft Palate-Craniofacial Assoc. févr 2021;58(2):163‑9.
Akhiwu BI, Efunkoya AA, Akhiwu HO, Adebola RA. Congenital Heart Disease in Cleft Lip and Palate Patients: How Common Is the Association? J Adv Oral Res. SAGE Publications India; 1 mai 2017;8(1‑2):53‑6.
Barrett WJ, Diedericks BJS, Barrett CL, Joubert G, Turton EW. Congenital heart defects in children with cleft lips and/or palates at an academic hospital in central South Africa. South Afr J Anaesth Analg. Medpharm Publications; avr 2019;25(2):23‑9.
Panamonta V, Pradubwong S, Panamonta M, Chowchuen B. Prevalence of Congenital Heart Diseases in Patients with Orofacial Clefts: A Systematic Review. J Med Assoc Thail Chotmaihet Thangphaet. août 2015;98 Suppl 7:S22-27.
Priyadharshini R, James S, Rathinasamy J, R. M, Gopalakrishnan G, Kharlukhi J. A cross-sectional study of cardiac anomalies among children with orofacial cleft - role of echocardiography. Int J Contemp Pediatr. 21 juin 2017;4(4):1274.