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RÉSUMÉ
Introduction. La pandémie à COVID-19 représente un problème mondial de santé publique. Nous réalisons cette étude pour décrire les aspects épidémiologiques, cliniques, thérapeutiques, évolutifs et pronostic de la COVID-19 à Bouaké. Patients et méthodes. Il s'agissait d'une étude transversale rétrospective analytique menée du 27 Janvier 2021 au 27 janvier 2022 au centre COVID de Bouaké. La population d’étude était constituée de tous les patients infectés par le COVID-19 et reçus au centre. La recherche de facteurs de risque de mortalité a été faite par régression logistique avec le model de Cox et un seuil de significativité 0,05. Résultats. Nous avons retenu 779 patients. Leur âge médian était de 41 ans et le sex-ratio était de 1. Parmi eux 300 patients (38,5%) avaient une comorbidité et 503 patients (64,6%) étaient sujets contacts. Les principaux signes étaient la toux (69,4%), l’asthénie (44,7%) et la fièvre (34,1%). Les modalités thérapeutiques étaient le confinement à domicile pour 596 patients (76,5%) et l’hospitalisation pour 183 patients (23,5%). La durée médiane de confinement était de 13 jours. L’évolution était marquée par la guérison dans 92,9% des cas. Les facteurs de risque de mortalité étaient l’âge (p<0,001), la comorbidité (0,043), la dyspnée (p=0,001), la fièvre (p=0,009) et le coma (p=0,020). Conclusion. La COVID-19 touche préférentiellement l’adulte jeune, avec ou sans antécédent pathologique. La létalité est faible. Les facteurs de risque de mortalité étaient l’âge, la comorbidité, la dyspnée, la fièvre et le coma.
ABSTRACT
Introduction. The COVID-19 pandemic is a global public health problem. We are carrying out this study to describe the epidemiological, clinical, therapeutic, evolutionary and prognostic aspects of COVID-19 in Bouaké. Patients and methods. This was an analytical retrospective cross-sectional study conducted from January 27, 2021 to January 27, 2022 at the Bouaké COVID center. The study population consisted of all patients infected with COVID-19 and received at the center. The search for mortality risk factors was done by logistic regression with the Cox model and a significance level of 0.05. Results. We retained 779 patients. Their median age was 41 years and the sex ratio was 1. Among them, 300 patients (38.5%) had a comorbidity and 503 patients (64.6%) were contact subjects. The main signs were cough (69.4%), asthenia (44.7%) and fever (34.1%). The therapeutic modalities were home confinement for 596 patients (76.5%) and hospitalization for 183 patients (23.5%). The median duration of confinement was 13 days. The evolution was marked by healing in 92.9% of cases. Mortality risk factors were age (p<0.001), comorbidity (0.043), dyspnea (p=0.001), fever (p=0.009) and coma (p=0.020). Conclusion. COVID-19 preferentially affects young adults, with or without a pathological history. Lethality is low. Mortality risk factors were age, comorbidity, dyspnoea, fever and coma.

Keywords

épidémiologie, Coronavirus, SARS-Cov2, Bouaké epidemiology, Coronavirus, SARS-Cov2, Bouaké

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Kone Djakaridja, Kadiané-Oussou NJ, Kone S, Yapo MT, Kaidioula JM, Aba YT, Ouattara B, & Kra O. (2023). Aspects Épidémiologiques, Cliniques, Thérapeutiques et Pronostiques de la COVID-19 chez l’Adulte à Bouake (Côte d’Ivoire). HEALTH SCIENCES AND DISEASE, 24(4). https://doi.org/10.5281/hsd.v24i4.4291
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