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Abstract
RÉSUMÉ
Objectif. Déterminer la prévalence de la sarcopénie et les facteurs qui lui sont associés chez des sujets Camerounais âgés de 55 ans et plus. Population et méthodes. Une étude prospective transversale a inclus des patients âgés de 55 ans et plus admis dans un service de Médecine Interne et spécialités. Les seuils retenus pour définir la sarcopénie étaient une force de préhension de moins de 20kg chez la femme et moins de 30kg chez l’homme. Les données ont été encodées et analysées à l’aide du logiciel SPSS version 20. Nous avons inclus dans le modèle d’analyse multivarié les variables avec un p<0,2. Le seuil de significativité était p<0,05. Résultats. Au total, 88 patients ont été inclus dans l’analyse avec une majorité de femmes (n=46, 52,3%) et une moyenne d’âge de 66,4 ans. Les principaux syndromes gériatriques étaient la dépendance pour les activités de la vie quotidienne (70,5%), la polypharmacie (29,5%), la dénutrition (17%) et les chutes (13,6%). La force de préhension moyenne était de 30,4kg chez les hommes et de 18,7kg chez les femmes (p<0,001). Au total, 47 patients (53,4%) avaient une sarcopénie et les facteurs indépendamment associés étaient un âge ≥ 75ans (p=0,023 ; OR 6,5 IC95% 1,2-35,4) et un SARC-F ≥ 4 (p=0,005 ; OR 6,2 IC95% 1,7-22,3). Conclusion. La sarcopénie est fréquente chez les personnes âgées hospitalisées en médecine interne au Cameroun.
ABSTRACT
Objective. To determine the prevalence of sarcopenia and factors associated with it in a group of Cameroonian subjects ages 55 yeas od more. Population and methods. A prospective cross-sectional study included patients aged 55 years and older admitted to a department of internal medicine and specialties. The thresholds used to define sarcopenia were a grip strength of less than 20kg in women and less than 30kg in men. Data were coded and analyzed using SPSS version 20 software. We included in the multivariate analysis model the variables with a p<0.2. The threshold for significance was p<0.05. Results. A total of 88 patients were included in the analysis with a majority of women (n=46, 52.3%) and an average age of 66.4 years. The main geriatric syndromes were dependence for activities of daily living (70.5%), polypharmacy (29.5%), undernutrition (17%) and falls (13.6%). The mean grip strength was 30.4kg in men and 18.7kg in women (p<0.001). A total of 47 patients (53.4%) had sarcopenia and the independently associated factors were age ≥ 75y (p=0.023; OR 6.5 CI95% 1.2-35.4) and SARC-F ≥ 4 (p=0.005; OR 6.2 CI95% 1.7-22.3). Conclusion. Sarcopenia is common in elderly internal medicine inpatients n Cameroon.
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References
- Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, et al. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010;39(4):412‑23.
- Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48(1):16‑31.
- Shaw SC, Dennison EM, Cooper C. Epidemiology of Sarcopenia: Determinants Throughout the Lifecourse. Calcif Tissue Int. 2017;101(3):229‑47.
- Janssen I, Shepard DS, Katzmarzyk PT, Roubenoff R. The healthcare costs of sarcopenia in the United States. J Am Geriatr Soc. 2004;52(1):80‑5.
- Leong DP, Teo KK, Rangarajan S, Lopez-Jaramillo P, Avezum A, Orlandini A, et al. Prognostic value of grip strength: findings from the Prospective Urban Rural Epidemiology (PURE) study. Lancet Lond Engl. 2015;386(9990):266‑73.
- Kim H, Hirano H, Edahiro A, Ohara Y, Watanabe Y, Kojima N, et al. Sarcopenia: Prevalence and associated factors based on different suggested definitions in community-dwelling older adults. Geriatr Gerontol Int. 2016;16 Suppl 1:110‑22.
- Ethgen O, Beaudart C, Berckinx F, Bruyère O, Reginster JY, et al. The future prevalence of sarcopenia in Europe: A claim for public health action. Calcif Tissue Int. 2017; 100(3):229-34.
- Adebusoye LA, Ogunbode AM, Olowookere OO, Ajayi SA, Ladipo MM. Factors associated with sarcopenia among older patients attending a geriatric clinic in Nigeria. Niger J Clin Pract. 2018;21(4):443‑50.
- Senior HE, Henwood TR, Beller EM, Mitchell GK, Keogh JWL. Prevalence and risk factors of sarcopenia among adults living in nursing homes. Maturitas. 2015;82(4):418‑23.
- Liu P, Hao Q, Hai S, Wang H, Cao L, Dong B. Sarcopenia as a predictor of all-cause mortality among community-dwelling older people: A systematic review and meta-analysis. Maturitas. 2017;103:16‑22.
- Ntsama EM, Atsa D, Zogo Noah D, Zingui Ottou M, Paula G, Nkeck JR, et al. Geriatric syndromes in an urban elderly population in Cameroon: a focus on disability, sarcopenia and cognitive impairment. Pan Afr Med J 2020; 11(37):229.
- Moyou E. Cameroun - Espérance de vie à la naissance (année) | Statistiques [Internet]. 2020 [cité 12 avr 2020]. (Statista). Disponible sur: http://perspective.usherbrooke.ca/bilan/servlet/BMTendanceStatPays?langue=fr&codePays=CMR&codeStat=SP.DYN.LE00.IN&codeStat2=x
- Koopman JJE, van Bodegom D, van Heemst D, Westendorp RGJ. Handgrip strength, ageing and mortality in rural Africa. Age Ageing. i 2015;44(3):465‑70.
- Smoliner C, Sieber CC, Wirth R. Prevalence of sarcopenia in geriatric hospitalized patients. J Am Med Dir Assoc. 2014;15(4):267‑72.
- Diz JBM, Queiroz BZ de, Tavares LB, Pereira LSM, Diz JBM, Queiroz BZ de, et al. Prevalence of sarcopenia among the elderly: findings from broad cross-sectional studies in a range of countries. Rev Bras Geriatr E Gerontol. 2015;18(3):665‑78.
- Rossi AP, Fantin F, Micciolo R, Bertocchi M, Bertassello P, Zanandrea V, et al. Identifying sarcopenia in acute care setting patients. J Am Med Dir Assoc. 2014;15(4):303.e7-12.
- Sousa-Santos AR, Afonso C, Borges N, Santos A, Padrão P, Moreira P, et al. Factors associated with sarcopenia and undernutrition in older adults. Nutr Diet J Dietit Assoc Aust. 2019;76(5):604‑12.
- Malmstrom TK, Miller DK, Simonsick EM, Ferrucci L, Morley JE. SARC-F: a symptom score to predict persons with sarcopenia at risk for poor functional outcomes. J Cachexia Sarcopenia Muscle. 2016;7(1):28‑36.
- Ida S, Kaneko R, Murata K. SARC-F for Screening of Sarcopenia Among Older Adults: A Meta-analysis of Screening Test Accuracy. J Am Med Dir Assoc. 2018;19(8):685‑9.
- Malmstrom TK, Morley JE. SARC-F: a simple questionnaire to rapidly diagnose sarcopenia. J Am Med Dir Assoc. 2013;14(8):531‑2.
References
Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, et al. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010;39(4):412‑23.
Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48(1):16‑31.
Shaw SC, Dennison EM, Cooper C. Epidemiology of Sarcopenia: Determinants Throughout the Lifecourse. Calcif Tissue Int. 2017;101(3):229‑47.
Janssen I, Shepard DS, Katzmarzyk PT, Roubenoff R. The healthcare costs of sarcopenia in the United States. J Am Geriatr Soc. 2004;52(1):80‑5.
Leong DP, Teo KK, Rangarajan S, Lopez-Jaramillo P, Avezum A, Orlandini A, et al. Prognostic value of grip strength: findings from the Prospective Urban Rural Epidemiology (PURE) study. Lancet Lond Engl. 2015;386(9990):266‑73.
Kim H, Hirano H, Edahiro A, Ohara Y, Watanabe Y, Kojima N, et al. Sarcopenia: Prevalence and associated factors based on different suggested definitions in community-dwelling older adults. Geriatr Gerontol Int. 2016;16 Suppl 1:110‑22.
Ethgen O, Beaudart C, Berckinx F, Bruyère O, Reginster JY, et al. The future prevalence of sarcopenia in Europe: A claim for public health action. Calcif Tissue Int. 2017; 100(3):229-34.
Adebusoye LA, Ogunbode AM, Olowookere OO, Ajayi SA, Ladipo MM. Factors associated with sarcopenia among older patients attending a geriatric clinic in Nigeria. Niger J Clin Pract. 2018;21(4):443‑50.
Senior HE, Henwood TR, Beller EM, Mitchell GK, Keogh JWL. Prevalence and risk factors of sarcopenia among adults living in nursing homes. Maturitas. 2015;82(4):418‑23.
Liu P, Hao Q, Hai S, Wang H, Cao L, Dong B. Sarcopenia as a predictor of all-cause mortality among community-dwelling older people: A systematic review and meta-analysis. Maturitas. 2017;103:16‑22.
Ntsama EM, Atsa D, Zogo Noah D, Zingui Ottou M, Paula G, Nkeck JR, et al. Geriatric syndromes in an urban elderly population in Cameroon: a focus on disability, sarcopenia and cognitive impairment. Pan Afr Med J 2020; 11(37):229.
Moyou E. Cameroun - Espérance de vie à la naissance (année) | Statistiques [Internet]. 2020 [cité 12 avr 2020]. (Statista). Disponible sur: http://perspective.usherbrooke.ca/bilan/servlet/BMTendanceStatPays?langue=fr&codePays=CMR&codeStat=SP.DYN.LE00.IN&codeStat2=x
Koopman JJE, van Bodegom D, van Heemst D, Westendorp RGJ. Handgrip strength, ageing and mortality in rural Africa. Age Ageing. i 2015;44(3):465‑70.
Smoliner C, Sieber CC, Wirth R. Prevalence of sarcopenia in geriatric hospitalized patients. J Am Med Dir Assoc. 2014;15(4):267‑72.
Diz JBM, Queiroz BZ de, Tavares LB, Pereira LSM, Diz JBM, Queiroz BZ de, et al. Prevalence of sarcopenia among the elderly: findings from broad cross-sectional studies in a range of countries. Rev Bras Geriatr E Gerontol. 2015;18(3):665‑78.
Rossi AP, Fantin F, Micciolo R, Bertocchi M, Bertassello P, Zanandrea V, et al. Identifying sarcopenia in acute care setting patients. J Am Med Dir Assoc. 2014;15(4):303.e7-12.
Sousa-Santos AR, Afonso C, Borges N, Santos A, Padrão P, Moreira P, et al. Factors associated with sarcopenia and undernutrition in older adults. Nutr Diet J Dietit Assoc Aust. 2019;76(5):604‑12.
Malmstrom TK, Miller DK, Simonsick EM, Ferrucci L, Morley JE. SARC-F: a symptom score to predict persons with sarcopenia at risk for poor functional outcomes. J Cachexia Sarcopenia Muscle. 2016;7(1):28‑36.
Ida S, Kaneko R, Murata K. SARC-F for Screening of Sarcopenia Among Older Adults: A Meta-analysis of Screening Test Accuracy. J Am Med Dir Assoc. 2018;19(8):685‑9.
Malmstrom TK, Morley JE. SARC-F: a simple questionnaire to rapidly diagnose sarcopenia. J Am Med Dir Assoc. 2013;14(8):531‑2.