Artériopathie Oblitérante Asymptomatique des Membres Inférieurs chez un Groupe de Patients avec des Facteurs de Risque Cardiovasculaire à Yaoundé

Alain Menanga, B Hamadou, AJ Ahinaga, G E Guegang, H Hakapoka, A Yomba, C Nkoké, P Mintom, J Boombhi, E Wawo, S Kingué

Abstract


INTRODUCTION
L’artériopathie oblitérante des membres inférieurs (AOMI) évolue chez près de 70% des malades de manière asymptomatique. Le but de notre étude était de décrire les aspects épidémiologiques, cliniques et diagnostiques de l’AOMI chez un groupe de patients consultant à l’Hôpital Général de Yaoundé.

METHODOLOGIE

Il s’agit d’une étude transversale, descriptive qui s’est déroulée d’Octobre 2012 à Avril 2013 dans l’unité de Cardiologie de l’Hôpital général de Yaoundé. Nous avons recruté 42 sujets ayant au moins un facteur de risque cardiovasculaire majeur. Pour chaque sujet, nous avons collecté des données cliniques, anthropométriques. Puis nous avons mesuré l’Indice des pressions systoliques(IPS) et l’épaisseur intima média (EIM) fémorale.
RESULTATS
La moyenne d’âge des sujets était de 54,3 ± 10,3 ans avec un sex-ratio (H/F) de 3,2. Une AOMI (IPS < 0,90) a été retrouvée chez 16,7% des sujets, tandis que 7,1% avaient un IPS > 1,30. L’EIM fémorale moyenne était de 0,82 ± 0,19 mm et 26,2% des sujets avaient une EIM augmentée (> 1 mm).
CONCLUSION
L’AOMI asymptomatique est fréquente chez les patients présentant plusieurs facteurs de risque cardiovasculaire à Yaoundé.


ABSTRACT
INTRODUCTION
Peripheral arterial disease (PAD) is a vascular disease that evolves in a latent form in about 70% of the patients. The aim of the study was to describe the epidemiological, clinical and diagnostic aspects of PAD in a group of patients at the Yaounde General Hospital.
METHODOLOGY
This was a cross-sectional, descriptive and analytic study which extended from October 2012 to April 2013 at the Cardiology unit of the Yaounde General Hospital. We recruited a total of 42 subjects having at least one major cardiovascular risk factor. For every patient, we collected clinical and anthropometric data. Then, we measured the ankle brachial index (ABI) and the femoral artery intima media thickness (IMT). Statistical analysis was done using appropriate tests in the SPSS 17.0 and STATA 11.1 soft ware.
RESULTS
The mean age was 54.3 ± 10.3 years with a sex ratio (M/F) 3.2. PAD (ABI < 0.9) was found in 16.7% of the subjects, whereas, 7.1% had an ABI > 1.3. The population’s mean femoral artery IMT was 0.82 ± 0.19 mm and 26.2% of the subjects had an increased IMT (> 1 mm).
CONCLUSION
Asymptomatic PAD is common among patients who present with cardiovascular risk factors in Yaounde.


Keywords


Peripheral artery disease-Ankle brachial index-Intima media thickness-Cardiovascular risk factor

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References


Organisation Mondiale de la Santé. Maladies cardiovasculaires, statistiques Septembre 2011.

Pande RL, Perlstein TS, Beckman JA et al. Secondary prevention and mortality in peripheral artery disease: National Health and Nutrition Examination Study, 1999 to 2004.

Circulation 2011 Jul 5;124(1):17-23.

Kummar A, Mash B, Rupesinghe G. Peripheral artery disease- High prevalence in rural black south Africans. S Afr Med Journal 2007; 97 (4): 285-8.

Cimmininello C, Kownator S, Kranedonk et al. The PANDORA study: Peripheral arterial disease in patients with non-high cardiovascular risk. Intern Emerg Med 2011; 6: 509-19

Vicente I, Lahoz C, Taboada M et al. Ankle brachial index in patients with diabetes mellitus: prevalence and risk factors. Rev Clin Esp 2006; 206 (5): 225-9.

Kingue S, Kuaban C, Muna WF et al. Mise en évidence ultrasonographique de l'athérosclérose carotidienne chez l'adulte noir Camerounais à risque cardiovasculaire.

Ann Cardiol Angeiol 1998; 47 (10): 722-27.

Pessinaba S, Mbaye A, Kane A et al. Screening for asymptomatic peripheral arterial occlusive disease of the lower limbs by measuring the ankle-brachial index in the general population in Senegal. J Mal Vasc 2012 Jul; 37(4): 195-200.

Selvin E, Erlinger TP. Prevalence of and risk factors for peripheral arterial disease in the United States: Results from the National Health and Nutrition Examination Survey, 1999-2000. Circulation 2004; 110: 738-43.

Tavintharan S, Ning Cheung, Su Chi Lim et al. Prevalence and risk factors for peripheral artery disease in an Asian population with diabetes mellitus.

Diabetes and Vascular Disease Research 2009; 6(2): 80-6.

Schoul JM, Aranand B, Doumercre P et al. Comparison of risk factors in vascopatic angina without significant fixed coronary narrowing and no vascopatic angina.

Am J Cardiol, 1986; 37: 199-202.

Aboyans V, Lacroix P, Lebourdon A et al. The intra- and interobserver variability of ankle-arm blood pressure index according to its mode of calculation.

J Clin Epidemiol 2003; 56 : 215-20.

Mourad JJ, Cacoub P, Collet JP et al. Screening of unrecognized peripheral arterial disease (PAD) using ankle-brachial index in high cardiovascular risk patients free from symptomatic PAD. J Vasc Surg 2009; 50: 572-580.

Allan PL, Mowbray P, Fowkes FG et al. Relationship between carotid intima-media thickness and symptomatic and asymptomatic peripheral arterial disease.

The Edingburgh Artery Study. Stroke 1997; 28: 348-53.

Cambou JP, Kownator S, Cacoub P et al. Prevalence of unknown peripheral artery disease in patients with coronary disease, data in primary care from the IPSILON study.

Arch Cardiovasc dis 2009; 102 (8-9): 625-31.


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