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ABSTRACT
Introduction. Diabetes is a public health problem and its association with tuberculosis increases its morbidity and mortality. The objective of this paper is to report the frequency of tuberculosis and describe its clinical features in diabetic inpatients at the Abass Ndao Hospital of Dakar. Patients and methods. Our work was a cross-sectional, descriptive, study conducted from January 1st, 2010, to December 31st, 2021. It concerned hospitalized diabetic patients with associated tuberculosis infection. Sociodemographic, clinical, para-clinical and evolution data were collected. Results. The hospital prevalence of diabetes/tuberculosis association was 0.72% (43/5903), while among the diabetic patients, 37.7% had tuberculosis. In our population study, there were 58.13% of women (sex ratio HF = 0.72). The average age of the population was 40 [19-76] years. The average consultation delay time was 70.59 [3-365] days. Two patients had a notion of contage. The main reasons for consultation were fever 58.1% (n=25), poor general state 48.83% (n=21) and cough 44.18% (n=19). The mean blood glucose level was 2.825. Twenty-three (23) patients had glycaemia titer superior to 2 g/l. Ketoacidosis was present in 11 patients. Half of the patients had been diabetic for more than 10 years. Thirty six (36) patients (83.72%) had pulmonary tuberculosis and 9.30% (n=4) had extra pulmonary multifocal TB tuberculosis Anemia was found in 29 65.91% (n=29). The average length of hospitalization was 10.84 days. Four (4) deaths were recorded. Conclusion. Tuberculosis in diabetics is an important cause of morbidity and mortality.
RÉSUMÉ
Introduction. Le diabète constitue un problème de santé publique et son association avec la tuberculose augmente sa morbi-mortalité. L’objectif était d’étudier la fréquence de la TB et ses caractéristiques chez les diabétiques hospitalisés en médecine à l’hôpital Abass Ndao de Dakar. Patients et Méthodes. Il s’agit d’une étude transversale, descriptive menée du 01 janvier 2010 au 31 Décembre 2021. Elle portait sur les diabétiques hospitalisés atteints d’une tuberculose. Les données épidémiologiques, cliniques, para cliniques et évolutives ont été évaluées. Résultats. La fréquence de l’association diabète /tuberculose était de 0,72% (43/5903) et parmi les diabétiques, 37,7% étaient tuberculeux. Dans notre poluation d’étude, les femmes prédominaient avec 58,1% (sex-ratio de 0,72). Les femmes au foyer étaient majoritaires 30,2%(n=13). Par ailleurs, 20,9%(n=9) étaient sans profession. L’âge moyen était de 40 ans [19-76] ans. Le délai de consultation moyen était de 70,59jours [3 et 365]. Deux patients avaient une notion de contage. Les principaux motifs de consultation étaient la fièvre 58,1%(n=25), l’AEG 48,83%(n=21) et la toux 44,18%(n=19). La glycémie moyenne était de 2,825. Vingt-trois (23) avaient plus de 2g/l. Une acidocétose était notée chez 11 patients. La moitié des patients était diabétique depuis plus de 10 ans. Plus des 2/3 des patients 83,72%(n=36) avaient une Tuberculose pulmonaire et 9,30 % (n=4) une TB multifocale extra pulmonaire. L’anémie était retrouvée chez 65, 9% (n=29). La durée d’hospitalisation moyenne était de 10,84 jours. Quatre (4) décès étaient enregistrés. Conclusion. La tuberculose chez le diabétique est une importante cause de morbidité et de mortalité d’où l’intérêt de sa recherche systématique.

Keywords

Tuberculosis Diabetes Senegal Tuberculose Diabète Sénégal

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Ngom N F, Sow D, Diop C T, Diedhiou D, Ndour M A, Sarr A, Ndour M, & Ka O. (2022). Clinical Presentation and Evolution of Tuberculosis of Diabetic Patients Hospitalized at Abass Ndao Hospital from 2010 to 2021. HEALTH SCIENCES AND DISEASE, 23(5). https://doi.org/10.5281/hsd.v23i5.3614
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