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Abstract
RÉSUMÉ
Introduction. L’apoplexie hypophysaire est une urgence endocrinienne rare liée à un infarctus ou une hémorragie dans la glande hypophysaire. Elle implique l’existence d’un adénome hypophysaire connu ou non. Observation. Nous rapportons le cas d’un patient de 59 ans suivi pour insuffisance surrénalienne primaire suite à une surrénalectomie bilatérale indiquée pour masse surrénalienne. Pendant son suivi, il a présenté une apoplexie hypophysaire sur un macroadénome hypophysaire méconnu. Conclusion. Ce cas clinique met en exergue le contexte de découverte atypique d’un macroadénome hypophysaire, les difficultés diagnostiques et la nécessité d’une prise en charge multidisciplinaire systématique des patients en endocrinologie dans notre contexte.
ABSTRACT
Introduction. Pituitary apoplexy is a rare endocrine emergency caused by infarction or hemorrhage in the pituitary gland. It involves the presence of a known or unknown pituitary adenoma. Observation. We report the case of a 59-year-old patient followed for primary adrenal insufficiency following bilateral adrenalectomy indicated for an adrenal mass. During follow-up, he developed pituitary apoplexy on an unrecognized pituitary macroadenoma. Conclusion. This clinical case highlights the atypical discovery of a pituitary macroadenoma, the diagnostic challenges, and the need for a systematic multidisciplinary approach to the management of endocrine patients in our context.
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References
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- Falhammar H, Tornvall S, Höybye C. Pituitary Apoplexy: A Retrospective Study of 33 Cases From a Single Center. Frontiers in Endocrinology [Internet]. 2021 [cited 2023 Dec 3];12. Available from: https://www.frontiersin.org/articles/10.3389/fendo.2021.656950
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- Muthukumar N. Pituitary Apoplexy: A Comprehensive Review. Neurology India. 2020 Jan 6;68(7):72.
- Kanchana WGP, Kumarathunga P a. DM, Shakthilingham G, Antonypillai C, Gunatilake S, Karunasagara DD, et al. Laparoscopic Bilateral Adrenalectomy in a Young Female Patient with Recurrent Cushing’s Disease. Case Reports in Endocrinology. 2021 Feb 12;2021:e6632436.
- Maccora D, Walls G, Sadler G, Mihai R. Bilateral adrenalectomy: a review of 10 years’ experience. Ann R Coll Surg Engl. 2017 Feb;99(2):119–22.
- Guerin C, Taieb D, Treglia G, Brue T, Lacroix A, Sebag F, et al. Bilateral adrenalectomy in the 21st century: when to use it for hypercortisolism? Endocrine-Related Cancer. 2016 Feb 1;23(2):R131–42.
- Torres-Ríos JA, Romero-Luna G, Soto JMM, Zavala-Romero L, Maqueda MLA, Camacho AR, et al. Nelson’s Syndrome: A Narrative Review. Cureus [Internet]. 2023 May [cited 2023 Dec 3];15(5). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272858/
- Brandi ML, Agarwal SK, Perrier ND, Lines KE, Valk GD, Thakker RV. Multiple Endocrine Neoplasia Type 1: Latest Insights. Endocr Rev. 2021 Mar 15;42(2):133–70.
- Mokhtari ME, Dago K, Sode HC, Do L, Popescu M. Les Adénomes Hypophysaires non Fonctionnels dans la Population Noire Afrocaribéenne : Une étude de 48 Cas au CHU de Pointe-À-Pitre de Guadeloupe. HEALTH SCIENCES AND DISEASE [Internet]. 2019 Jun 30 [cited 2023 Dec 3];20(4). Available from: https://www.hsd-fmsb.org/index.php/hsd/article/view/1393
References
Ranabir S, Baruah MP. Pituitary apoplexy. Indian J Endocrinol Metab. 2011 Sep;15(Suppl3):S188–96.
Falhammar H, Tornvall S, Höybye C. Pituitary Apoplexy: A Retrospective Study of 33 Cases From a Single Center. Frontiers in Endocrinology [Internet]. 2021 [cited 2023 Dec 3];12. Available from: https://www.frontiersin.org/articles/10.3389/fendo.2021.656950
Glezer A, Bronstein MD. Pituitary apoplexy: pathophysiology, diagnosis and management. Arch Endocrinol Metab. 2015 Jun;59(3):259–64.
Muthukumar N. Pituitary Apoplexy: A Comprehensive Review. Neurology India. 2020 Jan 6;68(7):72.
Kanchana WGP, Kumarathunga P a. DM, Shakthilingham G, Antonypillai C, Gunatilake S, Karunasagara DD, et al. Laparoscopic Bilateral Adrenalectomy in a Young Female Patient with Recurrent Cushing’s Disease. Case Reports in Endocrinology. 2021 Feb 12;2021:e6632436.
Maccora D, Walls G, Sadler G, Mihai R. Bilateral adrenalectomy: a review of 10 years’ experience. Ann R Coll Surg Engl. 2017 Feb;99(2):119–22.
Guerin C, Taieb D, Treglia G, Brue T, Lacroix A, Sebag F, et al. Bilateral adrenalectomy in the 21st century: when to use it for hypercortisolism? Endocrine-Related Cancer. 2016 Feb 1;23(2):R131–42.
Torres-Ríos JA, Romero-Luna G, Soto JMM, Zavala-Romero L, Maqueda MLA, Camacho AR, et al. Nelson’s Syndrome: A Narrative Review. Cureus [Internet]. 2023 May [cited 2023 Dec 3];15(5). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10272858/
Brandi ML, Agarwal SK, Perrier ND, Lines KE, Valk GD, Thakker RV. Multiple Endocrine Neoplasia Type 1: Latest Insights. Endocr Rev. 2021 Mar 15;42(2):133–70.
Mokhtari ME, Dago K, Sode HC, Do L, Popescu M. Les Adénomes Hypophysaires non Fonctionnels dans la Population Noire Afrocaribéenne : Une étude de 48 Cas au CHU de Pointe-À-Pitre de Guadeloupe. HEALTH SCIENCES AND DISEASE [Internet]. 2019 Jun 30 [cited 2023 Dec 3];20(4). Available from: https://www.hsd-fmsb.org/index.php/hsd/article/view/1393