Main Article Content
Abstract
Abstract
Introduction
Heterotopic pregnancy or simultaneous pregnancy is defined as the association of intra-uterine pregnancy and extra-uterine pregnancy in the same patient. Formerly rare, the frequency of this simultaneous pregnancy has steadily increased with the appearance of medically assisted reproduction, or ovulation induction technics. The diagnosis is difficult, and occurs very late.
Objectives
The main objective of this study was to detect a case study of an HP in a 32 years old patient admitted to the hospital for a delayed abdominal pregnancy. After observations, a literature review was searched in order to better understand the epidemiological aspects, diagnosis and therapeutic of this unusual and cheated clinical pathology.
Observations
The patient had no trouble in the stomach, nor associated metrorragy. In her preceedings, she was nullipara, without abortion notion. Examination at the entrance showed a general normal state. The stomach was distended without peritoneal irritation signs, nor occlusive syndrome.
Results
The ultrasound revealed a delayed abdominal pregnancy of 26 weeks, and no sign of IUP. A scheduled laporotomy indicated a late and undisrupted left ampulla pregnancy with a fetal deformation, and an inserted placenta on the left annex of the gestated uterus. A left annexectomy was carried out with little manipulations of the uterus. The controlateral annex had no particularity. A tocolysis was realized during the first week post surgeon. Unfortunately, the operation led to a spontaneous abortion two weeks later.
Conclusion
If heterotopic pregnancy is rarely encountered in our country, its incidence is increasing in developed countries due to development of medically assisted reproduction. Our observations illustrate the diagnosis difficulties and the complexity of precautions taken in particular for intra-uterine pregnancy. A following up of pregnant women should be taken into consideration to guaranty a complete pregnancy without associated risks.
Key words: Heterotopic pregnancy, intra-uterine pregnancy, extra-uterine pregnancy, left annexectomy, etiopathogeny.
Résumé
Introduction
Une grossesse hétérotopique ou encore grossesse combinée se définit par une association d’une grossesse intra-utérine et d’une grossesse extra-utérine chez une même patiente. Autrefois fort rare, la fréquence de cette association ne cesse de croître depuis l’apparition de l’aide médicale à la procréation et des techniques d’induction de l’ovulation. Le diagnostic est difficile et tardif.
Objectifs
L’objectif principal de ce travail est de détecter un cas de un cas de grossesse hétérotopique chez une patiente de 32 ans admise dans le service pour grossesse abdominale arrêtée. A travers notre observation, une revue de la littérature a été faite pour mieux cerner les aspects épidémiologiques, diagnostic et thérapeutique de cette entité clinique rare et trompeuse.
Observations
Le patient n’avait ni trouble digestif ni métrorragie associée. Dans ses antécédents on note qu’elle est nullipare, sans notion d’avortement. Les cycles antérieurs étaient sans anomalies. L’examen à l’entrée notait un bon état général. L’abdomen était distendu sans signe d’irritation péritonéal ni du syndrome occlusif.
Résultats
L’échographie révélait une grossesse abdominale arrêtée de 26 semaines tout en méconnaissant une grossesse intra-utérine. Une laparotomie programmée avait permis de découvrir une grossesse ampullaire gauche tardive non rompu avec déformation du fœtus et insertion du placenta sur l’annexe gauche l’utérus était gravide. Une anexectomie gauche était réalisée avec une manipulation minime de l’utérus. L’annexe controlatérale était sans particularité. Une tocolyse était réalisé pendant la première semaine post-opératoire ; cependant les suites opératoires étaient marquées par une fausse couche spontanée dès la deuxième semaine après l’intervention.
Conclusion
Si la grossesse hétérotopique se rencontre rarement dans notre pays, son incidence est en nette progression dans les pays développés en rapport avec le développement de la procréation médicale assistée. Notre observation illustre les difficultés diagnostics et la complexité de sa prise en charge en particulier de la grossesse intra-utérine. Un suivi rapproché des femmes enceintes est de rigueur pour garantir une grossesse à terme sans risque.
Mots clés : Grossesse heterotopique, grossesse intra-ulterine, grossesse extra-ulterine, annexectomie gauche, ectopathogenie.
*Correspondence to
Dr. NGAROUA, Service de Chirurgie, Hôpital Régional de Ngaoundéré BP 45 ;Tel: (237) 99 97 83 51
Email:mdngaroua2007@yahoo.fr
Keywords
Article Details
References
- Duvernay GJ: Anatomic production, Joubert, Paris, France, 1781.
- Diallo D; Aubard Y; Piver P; Baudet JH: Heterotopic pregnancy: based on 5 cases study and literature review. Journal of Gynecology Obstetric and Biology of Reproduction 2000, 29: 131-41.
- Montilla F; Amar P; Boyer S; Karoubi R; Diquelou IY: Heterotopic pregnancy: based on one case in a rare clinical table. Journal of Gynecology Obstetric and Biology of Reproduction 2007, 36(3): 302-5.
- Engongah-Beka T; Meyer JF; Ozouaki F; Sima-Ole B: Association of disrupted intra-uterine and extra-uterine pregnancy: based on 2 cases study with different evolutions and literature review. Médecine d’Afrique Noire 1997, 44: 8-9.
- Sepou A; Yanza MC; Nguembi E; Goddot M; Ngbale R; Kouabosso A: Epidemiologic and clinical aspects of 116 extra-uterine pregnancy cases at the communal hospital of Bangui. Médecine d’Afrique Noire 2003, 50 (10): 405-12.
- Fivnat questionnaires: Risk factors of Extra-uterine pregnancy during medically assisted reproduction. Contraception fertility and sexuality 1993, 21(5): 358-61.
- Tancer ML; Delke I; Veridiano NP: A fifteen year experience with ectopic pregnancy. Surgery and Gynecology Obstetric 1981, 152: 179-82.
- Tal J; Haddad S; Gordon N; Timor-Tritsu I: Heterotopic pregnancy after ovulation induction and assisted reproductive technologies: a literature review from 1971 to 1993. Fertility and Sterility 1996, 66: 1-12.
- Guirguis RR: Simultaneous intra-uterine and ectopic pregnancies following in vitro fertilization and gamete intrafallopian transfer. A review of nine cases. Human Reproduction 1990, 5: 484-6.
- Baker VL; Givens CR; Cadieux MC: Transvaginal reduction of an interstitiel heterotopic pregnancy with preservation of the intra uterine gestation. American Journal of Obstetric Gynecology 1997, 176: 1384-5.
- Molloy D; Deambrosis W; Keeping D; Multiple sited (heterotopic) pregnancy after in vitro fertilization and gamete intra fallopian transfer. Fertility and Sterility 1990, 53: 1068.
- Dicker D; Goldman G; Feldberg D; Ashchkenazi J; Goldman J: Heterotopic pregnancy after IVF-ET: report of a case and a review of the literature. Human Reproduction 1989, 4: 335.
References
Duvernay GJ: Anatomic production, Joubert, Paris, France, 1781.
Diallo D; Aubard Y; Piver P; Baudet JH: Heterotopic pregnancy: based on 5 cases study and literature review. Journal of Gynecology Obstetric and Biology of Reproduction 2000, 29: 131-41.
Montilla F; Amar P; Boyer S; Karoubi R; Diquelou IY: Heterotopic pregnancy: based on one case in a rare clinical table. Journal of Gynecology Obstetric and Biology of Reproduction 2007, 36(3): 302-5.
Engongah-Beka T; Meyer JF; Ozouaki F; Sima-Ole B: Association of disrupted intra-uterine and extra-uterine pregnancy: based on 2 cases study with different evolutions and literature review. Médecine d’Afrique Noire 1997, 44: 8-9.
Sepou A; Yanza MC; Nguembi E; Goddot M; Ngbale R; Kouabosso A: Epidemiologic and clinical aspects of 116 extra-uterine pregnancy cases at the communal hospital of Bangui. Médecine d’Afrique Noire 2003, 50 (10): 405-12.
Fivnat questionnaires: Risk factors of Extra-uterine pregnancy during medically assisted reproduction. Contraception fertility and sexuality 1993, 21(5): 358-61.
Tancer ML; Delke I; Veridiano NP: A fifteen year experience with ectopic pregnancy. Surgery and Gynecology Obstetric 1981, 152: 179-82.
Tal J; Haddad S; Gordon N; Timor-Tritsu I: Heterotopic pregnancy after ovulation induction and assisted reproductive technologies: a literature review from 1971 to 1993. Fertility and Sterility 1996, 66: 1-12.
Guirguis RR: Simultaneous intra-uterine and ectopic pregnancies following in vitro fertilization and gamete intrafallopian transfer. A review of nine cases. Human Reproduction 1990, 5: 484-6.
Baker VL; Givens CR; Cadieux MC: Transvaginal reduction of an interstitiel heterotopic pregnancy with preservation of the intra uterine gestation. American Journal of Obstetric Gynecology 1997, 176: 1384-5.
Molloy D; Deambrosis W; Keeping D; Multiple sited (heterotopic) pregnancy after in vitro fertilization and gamete intra fallopian transfer. Fertility and Sterility 1990, 53: 1068.
Dicker D; Goldman G; Feldberg D; Ashchkenazi J; Goldman J: Heterotopic pregnancy after IVF-ET: report of a case and a review of the literature. Human Reproduction 1989, 4: 335.