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Abstract

ABSTRACT
Background and objective. Neonatal mortality remains high in low-income countries. Mortality risk of low birthweight (LBW) is the highest. With aim to describe trends on mortality and death causes of LBW in a neonatal care centre in a 7 years period, we did the present study. Methods. We did an observational retrospective study in a single care centre. This study population comprised all LBW infants admitted to the unit, from 2009 to 2016, weighing < 2500 g irrespective of gestational age. The main outcome was the percentage of LBW infants discharged alive during the study period. We also noted the diagnosis related to death of those who died before discharge. Results. During the study period, 10590 newborns were admitted in neonatology unit from which 2625 (24.78%) had LBW. Nine LBW on ten were discharged alive. The main causes of death were neonatal infection, complications of birth asphyxia and congenital malformations. Conclusion. Mortality rate of LBW neonates in our centre is 9.1%. The main causes of death are neonatal infections, birth asphyxia and surgical emergencies. Advocacy to improve quality of care together with a strong neonatal network may be helpful to reduce in-hospital neonatal mortality.
RÉSUMÉ
Introduction. La mortalité néonatale est élevée dans les pays à ressources limitées et elle est encore plus élevée en cas de petit poids de naissance (PPN). L’objectif de ce travail est de décrire l’évolution et les causes de la mortalité néonatale dans une structure de santé de référence de Yaoundé sur une période de sept ans. Méthodes. Il s’agit d’ue étude transversale descriptive et analytique effectuée au entre mère enfant de la fondation chant Biya de Yaoundé. Nous avons inclus tous les enfants admis dans ce centre, avec un poids de naissance de 2500 G, quel que soit l^’âge gestationnel à l’accouchement. Nos variables d’intérêt étaient l’état à la sortie (vivant ou mort) et la cause du décès éventuel. Résultats. Au cours de la période d’étude, 10590 nouveau-nés ont été admis au service de néonatalogie et 2625 (24.78%) avaient un petit poids de naissance.  La mortalité moyenne de la période était de 9.1% (8 à 24%). Les trois principales causes de mortalité étaient  l’infection néonatale, l’asphyxie néonatale et les malformations congénitales. Conclusion. La mortalité néonatale moyenne des enfants à petit poids de naissance est de 9.1%. Les principales causes de mortalité sont l’infection néonatale, les complications de l’asphyxie néonatale et les malformations congénitales chirurgicales. Pour réduire ces chiffres, des efforts orientés vers l’amélioration des soins d’urgence aux nouveau-nés associés à une mise en réseau des structures de soins sont nécessaires.

Keywords

Neonatal mortality low birthweight neonatal infections birth asphyxia Cameroon

Article Details

How to Cite
Sap Ngo Um, S., Kana, S. P., Ngo Njock, V., Abondo, G., & Koki, P. O. (2020). Mortality of Low Birth Weight Neonates in a Tertiary Care Centre of Yaounde (Cameroon). HEALTH SCIENCES AND DISEASE, 21(2). https://doi.org/10.5281/hsd.v21i2.1828

References

  1. National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications. Lancet 2012; 379: 2162–724.
  2. Lawn J, Kerber K, Enweronu-Laryea C, Massee Bateman O. Newborn survival in low resource settings-are we delivering? Br J Obstet Gynaecol. 2009;116 (1):49-59
  3. You D, Hug L, Ejdemyr S. Global, regional, and national levels and trends in under-5 mortality between 1990 and 2015, with scenario-based projections to 2030: a systematic analysis by the UN Inter-agency Group for child mortality estimation. Lancet (2015) 386:2275–86. doi: 10.1016/S0140-6736(15)00120-8
  4. Liu L, Oza S, Hogan D, Chu Y, Perin J, Zhu J, et al. Global, regional, and national causes of under-5 mortality in 2000-15: an updated systematic analysis with implications for the Sustainable Development Goals. Lancet. 2016;388(10063):3027-35.
  5. National institute of statistics and the DHS program (ICF). 2019. Demographic and Health survey of Cameroon 2018. Key Indicators. Yaoundé, Cameroon, and Rockville, Maryland, USA: INS and ICF. Available on http://www.measuredhs.com/publications
  6. Njom Nlend AE, Zeudja C, Ndiang S, Nga Motaze A, Ngassam L, Nsoa L. Trends in neonatal mortality of very-low-birth-weight infants between 1998 and 2013 in Essos Hospital, Yaounde, Cameroon. Arch Ped 2016;23:895-8
  7. Ray JG, Park AL, Fell DB. Mortality in Infants Affected by Preterm birth and Severe Small for-Gestational Age Birth Weight. Pediatrics. 2017;140(6):e20171881
  8. Baer RJ, Rogers EE, Partridge JC et al. Population-based risks of mortality and preterm morbidity by gestational age and birth weight. J Perinatol. 2016 Nov; 36(11):1008-13. doi: 10.1038/jp.2016.118
  9. Zou L, Wang X, Ruan Y et al. Preterm birth and neonatal mortality in China in 2011. Int J Gynaeco Obstet 2014;127(3):243-7. doi: 10.1016/j.ijgo.2014.06.018
  10. Yé D, Dao L, Néboua D et al. Morbidité et mortalité néonatales de 2002 à 2006 au centre hospitalier universitaire pédiatrique Charles de Gaulle de Ouagadougou (Burkina Faso). Cahier d’études et de recherches francophones / Santé 2008.17 (4) : 187-191
  11. Sylla M, Folquet Amorissani M, Oumar AA et al. Morbidité et mortalité néonatales dans le service de réanimation pédiatrique de l’hôpital Gabriel Touré. Louvain médical 2009; 128 (4) :141-4
  12. Koki Ndombo PO, Mua Ekei Q, Noutakdie Tochie J et al. A cohort analysis of neonatal hospital mortality rate and predictors of neonatal mortality in a sub-urban hospital of Cameroon. Italian Journal of Pediatrics (2017): 43:52
  13. Cissé T, Yacoubou Y, Ndiaye O et al. Time course of neonatal precocious mortality between 1994 and 2003 at the Dakar University Teaching Hospital. J Gynecol Obstet Biol Rep (Paris) 2006 feb;35(1):46-52.
  14. WHO. Standards for improving quality of maternal and newborn care in health facilities. Geneva 2017; Available on http://apps.who.int/iris
  15. Brahmbhatt H, Kigozi G, Wabwire-Mangen F et al. Mortality in HIV-infected and uninfected children of HIV-infected and uninfected mothers in rural Uganda. J Acquir Immune Defic Syndr. 2006 Apr 1;41(4):504-8.
  16. Kuhn L, Kasonde P, Sinkala M et al. Does severity of HIV disease in HIV-infected mothers affect mortality and morbidity among their uninfected infants? Clin Infect Dis. 2005 Dec 1;41(11):1654-61. Epub 2005 Oct 27.
  17. González R, Rupérez M, Sevene E et al. Effects of HIV infection on maternal and neonatal health in southern Mozambique: A prospective cohort study after a decade of antiretroviral drugs roll out. Plos One 2017 Jun 2;12(6):e0178134. doi: 10.1371/journal.pone.0178134. eCollection 201

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