Main Article Content
Abstract
RÉSUMÉ
La gangrène périphérique symétrique (GPS) est définie comme une lésion ischémique distale symétrique sur deux sites ou plus en l'absence d'obstruction des gros vaisseaux. Elle est rarement associée au paludisme. Nous rapportons un cas de GPS compliquant une infection à Plasmodium falciparum chez une fillette de 3 ans vivant en zone endémique. L’examen clinique initial révélait une hyperthermie, un Blantyre coma score à 3, une détresse respiratoire, une stabilité hémodynamique, une hépatomégalie douloureuse et une acrocyanose des 4 extrémités. L’hyperparasitémie devrait attirer l’attention des praticiens en charge des patients atteints de paludisme afin d’être à l'affût de la GPS.
ABSTRACT
The symmetrical peripheral gangrene (SPG) is defined as a symmetrical ischemic distal lesion on two sides or more when there is no obstruction of great vessels. It is scarcely related to malaria. We deal with a case of SPG complicating an infection of Falciparum plasmodium on a 3 years old girl living in an endemic area. Physical examination highlighted a hyperthermia, a Blantyre coma score at 3, a respiratory distress, a hepatomegalic pain and an acrocyanosis of the 4 extremities. Hyperparasitemy should raise doctor’s awareness on the hospital care of patients suffering from malaria in order to avoid SPG.
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References
- World Malaria Report. World Health Organization. 2011. Available from: http://www.who.int/entity/malaria/world_malaria_report_2011/9789241564403_eng.pdf].
- Rana A, Singh DP, Kaur G, Verma SK, Mahur H. Symmetrical peripheral gangrene : A rare complication of Plasmodium falciparum malaria. Trop Parasitol. 2015 Jul-Dec; 5(2): 130–2.
- Smaoui F, Koubaa M, Rekik K, et coll. La gangrène périphérique symétrique : à propos de 4 cas. Annales de Dermatologie et de Vénéréologie. 2018 :145(2) : 95-9.
- Abdali N, Malik AM, Kamal A, Ahmad M. Symmetrical peripheral gangrene due to Plasmodium falciparum malaria. BMJ Case Rep. 2014; 2014: bcr2014204268.
- Alkizim FO, Matheka D, Mwanda OW. Malaria complicated by gangrene : A case presentation and review. Pan Afr Med J. 2011; 10: 46.
- Shubhakaran KP. Gangrene in malaria revisited. Trop Parasitol. 2018 Jul-Dec; 8(2): 126.
- Gupta A, Dwivedi Y, Saxena AK, Joshi K. Symmetrical peripheral gangrene with Plasmodium falciparum malaria. J Nat Sci Biol Med. 2013 Jan-Jun; 4(1): 262–4.
- Rai SP , Neog LS , Bhattacharyya D and P Ganguli P. Symmetrical Peripheral Gangrene complicating Staphylococcal Toxic Shock Syndrome. Med J Armed Forces India. 2008 Apr; 64(2): 181–2.
- Dzeing-Ella A, Nze Obiang PC, Tchoua R, Planche T and all. Severe falciparum malaria in Gabonese children: clinical and laboratory features. Malar J. 2005 Jan 9;4:1.
- Tessier-Marteau A, Le Cruguel S, Grand F, P. Asfar et coll. CIVD et gangrène périphérique dans un cas de paludisme sévère : le cycle coagulation-inflammation appliqué au Plasmodium falciparum. Ann Biol Clin 2009 ; 67 (5) : 569-72.
- Thanachartwet V, Krudsood S, Wilairatana P and all. Peripheral gangrene in patients with severe falciparum malaria: report of 3 cases. Korean J. Parasitol.2006 June ; 44(2): 139-143.
- Masse E, Hantson P. Plasmodium falciparum malaria complicated by symmetrical peripheral gangrene, bowel ischemia, repeated candidemia, and bacteraemia. Hindawi Publishing Corporation Case Reports in Medicine. Volume 2014, Article ID 696725.
- Kumar P, Tansir G, Gupta H, Dixit J. Symmetrical peripheral gangrene in severe Plasmodium vivax malaria. Indian J Crit Care Med. 2017 Apr; 21(4): 245-6.
- Zaki SA, Shanbag P. Atypical manifestations of malaria.. Res Rep Trop Med. 2011; 2: 9–22.
- Musoke C, Ssendikadiwa C, Babua C, Schwartz JI. Severe falciparum malaria associated with massive pulmonary embolism. Annals of African Medicine,2014 ; 13(1) :47-9.
- Ghosh K, Shetty S. Blood coagulation in falciparum malaria: a review. Parasitol Res 2008 ; 102 : 571-6.
- Francischetti IMB, Seydel KB, Monteiro RQ, Whitten RO, Erexson CR, Noronha ALL, et al. Plasmodium falciparum-infected erythrocytes induce tissue factor expression in endothelial cells and support the assembly of multimolecular coagulation complexes. J Thromb Haemost. 2007 ; 5 : 155-65.
References
World Malaria Report. World Health Organization. 2011. Available from: http://www.who.int/entity/malaria/world_malaria_report_2011/9789241564403_eng.pdf].
Rana A, Singh DP, Kaur G, Verma SK, Mahur H. Symmetrical peripheral gangrene : A rare complication of Plasmodium falciparum malaria. Trop Parasitol. 2015 Jul-Dec; 5(2): 130–2.
Smaoui F, Koubaa M, Rekik K, et coll. La gangrène périphérique symétrique : à propos de 4 cas. Annales de Dermatologie et de Vénéréologie. 2018 :145(2) : 95-9.
Abdali N, Malik AM, Kamal A, Ahmad M. Symmetrical peripheral gangrene due to Plasmodium falciparum malaria. BMJ Case Rep. 2014; 2014: bcr2014204268.
Alkizim FO, Matheka D, Mwanda OW. Malaria complicated by gangrene : A case presentation and review. Pan Afr Med J. 2011; 10: 46.
Shubhakaran KP. Gangrene in malaria revisited. Trop Parasitol. 2018 Jul-Dec; 8(2): 126.
Gupta A, Dwivedi Y, Saxena AK, Joshi K. Symmetrical peripheral gangrene with Plasmodium falciparum malaria. J Nat Sci Biol Med. 2013 Jan-Jun; 4(1): 262–4.
Rai SP , Neog LS , Bhattacharyya D and P Ganguli P. Symmetrical Peripheral Gangrene complicating Staphylococcal Toxic Shock Syndrome. Med J Armed Forces India. 2008 Apr; 64(2): 181–2.
Dzeing-Ella A, Nze Obiang PC, Tchoua R, Planche T and all. Severe falciparum malaria in Gabonese children: clinical and laboratory features. Malar J. 2005 Jan 9;4:1.
Tessier-Marteau A, Le Cruguel S, Grand F, P. Asfar et coll. CIVD et gangrène périphérique dans un cas de paludisme sévère : le cycle coagulation-inflammation appliqué au Plasmodium falciparum. Ann Biol Clin 2009 ; 67 (5) : 569-72.
Thanachartwet V, Krudsood S, Wilairatana P and all. Peripheral gangrene in patients with severe falciparum malaria: report of 3 cases. Korean J. Parasitol.2006 June ; 44(2): 139-143.
Masse E, Hantson P. Plasmodium falciparum malaria complicated by symmetrical peripheral gangrene, bowel ischemia, repeated candidemia, and bacteraemia. Hindawi Publishing Corporation Case Reports in Medicine. Volume 2014, Article ID 696725.
Kumar P, Tansir G, Gupta H, Dixit J. Symmetrical peripheral gangrene in severe Plasmodium vivax malaria. Indian J Crit Care Med. 2017 Apr; 21(4): 245-6.
Zaki SA, Shanbag P. Atypical manifestations of malaria.. Res Rep Trop Med. 2011; 2: 9–22.
Musoke C, Ssendikadiwa C, Babua C, Schwartz JI. Severe falciparum malaria associated with massive pulmonary embolism. Annals of African Medicine,2014 ; 13(1) :47-9.
Ghosh K, Shetty S. Blood coagulation in falciparum malaria: a review. Parasitol Res 2008 ; 102 : 571-6.
Francischetti IMB, Seydel KB, Monteiro RQ, Whitten RO, Erexson CR, Noronha ALL, et al. Plasmodium falciparum-infected erythrocytes induce tissue factor expression in endothelial cells and support the assembly of multimolecular coagulation complexes. J Thromb Haemost. 2007 ; 5 : 155-65.