Holoprosencephalie à Caryotype Normal : Aspects Radiologiques à Propos d’un Cas à Ouagadougou

Nina-Astrid Nde/Ouedraogo, Bénilde Marie Ange Tiemtore Kambou, Moussa Zanga, Boubakar Ouattara, Ousséini Diallo, Rabiou Cisse

Abstract


ABSTRACT
Holoprosencephaly is a brain malformation resulting from a defect of median cleavage the embryonic brain; it is often associated with facial abnormalities. In this paper, the authors report the morphological aspects of a case of semi lobar holoprosencephaly without associated facial abnormalities that was discovered at second trimester obstetrical ultrasound. Karyotype and genetic explorations were normal.

RÉSUMÉ
L’holoprosencéphalie est une malformation cérébrale résultant d’un défaut de clivage médian du cerveau embryonnaire, souvent associée à des anomalies faciales.
A partir d’un cas, les auteurs rapportent les aspects à l’imagerie d’une holoprosencéphalie semi lobaire découverte à l’échographie du deuxième trimestre, sans anomalies faciales associées. Les explorations caryotypiques et génétiques sont revenues normales. Ils rappellent l’intérêt des explorations d’imagerie médicale dans le dépistage de cette affection.


Keywords


Holoprosencéphalie, semi lobaire, échographie, IRM, caryotype.KEY WORDS: semi lobar holoprosencephaly, ultrasound, MRI, karyotype

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References


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