Prévalence et Facteurs Associés d’Infertilité d’Origine Féminine au Centre Hospitalier de Recherche et d’Application en Chirurgie Endoscopique et Reproduction Humaine (CHRACERH), Yaoundé, Cameroun: Prevalence and associated factors of female infertility at the Hospital Centre for Endoscopic Surgery and Human Reproductive Research and Application, Yaounde, Cameroon

Abstract

Introduction. In 50% of cases, infertility can be explained by a female factor. The main objective of our study was to analyze female infertility according to the epidemiological and clinico-biological characteristics of women followed at the Hospital Center for Research and Application in Endoscopic Surgery and Human Reproduction. Methodology. A retrospective analytical cross-sectional study over a period from January 1, 2021 to December 31, 2023, i.e. 24 months, was carried out. In total, 406 files of women followed for couple infertility were consecutively included. The variables were compared using a Chi square test using SPSS version 27 software with a statistically significant threshold of p<5%.   Results and discussion. At least one female factor was found in 263/406 cases, or 64.8%, with the reduction in ovarian reserve predominating, or 176/263 (66.9%). FSH and LH values were higher in infertile women, i.e. 20.06±31.00 mIU/mL vs 11.04±13.00 mIU/mL (p=0.013) and 9.61±10.73 mIU/ mL vs 5.95±4.01 mIU/mL (p=0.012) however the mean AMH value was lower in them, i.e. 1.58±2.33 ng/mL vs 2.57±0.99 ng /mL (p<0.001). Age over 35 years, prolonged education levels, private sector of employment, STIs, pelvic surgery, genital Gardnerella vaginalis infection and pauciparity were factors associated with female infertility ( p<0.05). Conclusion. The female origin of infertility is predominant in our context with several associated factors. Its management requires multidisciplinary intervention