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Abstract
RÉSUMÉ
Deep neck infections are serious but treatable infections that affect the deep cervical spaces. Patients with deep neck abscesses present with high-grade fever, odynophagia, unilateral sore throat, or otalgia. Late diagnosis is a risk factor for poor outcomes due to a lack of effective diagnostic biological parameters. A correlation of procalcitonin with bacterial sepsis onset and severity has been reported. We present two cases in which procalcitonin levels effectively guided management. Procalcitonin is an affordable and reliable marker that could help diagnose and monitor patients with deep neck abscesses.
ABSTRACT
Les infections cervicales profondes sont des infections graves mais traitables qui affectent les espaces cervicaux profonds. Les patients présentant des abcès profonds du cou présentent une fièvre élevée, une odynophagie, un mal de gorge unilatéral ou une otalgie. Un diagnostic tardif est un facteur de risque de mauvais résultats en raison du manque de paramètres biologiques diagnostiques efficaces. Une corrélation entre la procalcitonine et l'apparition et la gravité du sepsis bactérien a été rapportée. Nous présentons deux cas dans lesquels les niveaux de procalcitonine ont efficacement guidé la prise en charge. La procalcitonine est un marqueur abordable et fiable qui pourrait aider à diagnostiquer et à surveiller les patients présentant des abcès profonds du cou.
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References
- Almuqamam M, Gonzalez FJ, Sharma S, Kondamudi NP (2024) Deep Neck Infections. In: StatPearls. StatPearls Publishing, Treasure Island (FL)
- McDowell RH, Hyser MJ (2024) Neck Abscess. In: StatPearls. StatPearls Publishing, Treasure Island (FL)
- Yanda A, Kobela M, Nansseu J, Taguebue J, Boula A, Eposse C, Monono N, Sap S, Gervaix A, Koki Ndombo P (2015) [Serum procalcitonin: A reliable tool for the diagnosis and follow-up of neonatal bacterial infections in Sub-Saharan Africa]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 22:. https://doi.org/10.1016/j.arcped.2015.05.017
- Huang DT, Yealy DM, Filbin MR, Brown AM, Chang C-CH, Doi Y, Donnino MW, Fine J, Fine MJ, Fischer MA, Holst JM, Hou PC, Kellum JA, Khan F, Kurz MC, Lotfipour S, LoVecchio F, Peck-Palmer OM, Pike F, Prunty H, Sherwin RL, Southerland L, Terndrup T, Weissfeld LA, Yabes J, Angus DC, ProACT Investigators (2018) Procalcitonin-Guided Use of Antibiotics for Lower Respiratory Tract Infection. N Engl J Med 379:236–249. https://doi.org/10.1056/NEJMoa1802670
- Cleland DA, Eranki AP (2024) Procalcitonin. In: StatPearls. StatPearls Publishing, Treasure Island (FL)
- Keïta A, Diallo I, Fofana M, Diallo MA, Diallo MMR, Balde O, Camara A, Sacko S (2020) Abcès rétropharyngé et la revue de la littérature: à propos de 5 observations. The Pan African Medical Journal 36:. https://doi.org/10.11604/pamj.2020.36.360.24282
- Ridder GJ, Technau-Ihling K, Sander A, Boedeker CC (2005) Spectrum and management of deep neck space infections: an 8-year experience of 234 cases. Otolaryngol Head Neck Surg 133:709–714. https://doi.org/10.1016/j.otohns.2005.07.001
- Robinson JO, Calandra T, Marchetti O (2005) [Utility of procalcitonin for the diagnosis and the follow-up of infections in febrile neutropenic patients]. Rev Med Suisse 1:878–882, 885–886
- Gervaix A, Pugin J (2005) Utilité du dosage plasmatique de la procalcitonine chez l’adulte et chez l’enfant. Rev Med Suisse 013:872–877
- Spahr L, Morard I, Hadengue A, Vadas L, Pugin J (2001) Procalcitonin is not an accurate marker of spontaneous bacterial peritonitis in patients with cirrhosis. Hepatogastroenterology 48:502–505
- Samama M-M, Germain D, Kamoun P, Collectif (2008) Précis de Biopathologie: Analyses médicales spécialisées. Biomnis, Lyon
References
Almuqamam M, Gonzalez FJ, Sharma S, Kondamudi NP (2024) Deep Neck Infections. In: StatPearls. StatPearls Publishing, Treasure Island (FL)
McDowell RH, Hyser MJ (2024) Neck Abscess. In: StatPearls. StatPearls Publishing, Treasure Island (FL)
Yanda A, Kobela M, Nansseu J, Taguebue J, Boula A, Eposse C, Monono N, Sap S, Gervaix A, Koki Ndombo P (2015) [Serum procalcitonin: A reliable tool for the diagnosis and follow-up of neonatal bacterial infections in Sub-Saharan Africa]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 22:. https://doi.org/10.1016/j.arcped.2015.05.017
Huang DT, Yealy DM, Filbin MR, Brown AM, Chang C-CH, Doi Y, Donnino MW, Fine J, Fine MJ, Fischer MA, Holst JM, Hou PC, Kellum JA, Khan F, Kurz MC, Lotfipour S, LoVecchio F, Peck-Palmer OM, Pike F, Prunty H, Sherwin RL, Southerland L, Terndrup T, Weissfeld LA, Yabes J, Angus DC, ProACT Investigators (2018) Procalcitonin-Guided Use of Antibiotics for Lower Respiratory Tract Infection. N Engl J Med 379:236–249. https://doi.org/10.1056/NEJMoa1802670
Cleland DA, Eranki AP (2024) Procalcitonin. In: StatPearls. StatPearls Publishing, Treasure Island (FL)
Keïta A, Diallo I, Fofana M, Diallo MA, Diallo MMR, Balde O, Camara A, Sacko S (2020) Abcès rétropharyngé et la revue de la littérature: à propos de 5 observations. The Pan African Medical Journal 36:. https://doi.org/10.11604/pamj.2020.36.360.24282
Ridder GJ, Technau-Ihling K, Sander A, Boedeker CC (2005) Spectrum and management of deep neck space infections: an 8-year experience of 234 cases. Otolaryngol Head Neck Surg 133:709–714. https://doi.org/10.1016/j.otohns.2005.07.001
Robinson JO, Calandra T, Marchetti O (2005) [Utility of procalcitonin for the diagnosis and the follow-up of infections in febrile neutropenic patients]. Rev Med Suisse 1:878–882, 885–886
Gervaix A, Pugin J (2005) Utilité du dosage plasmatique de la procalcitonine chez l’adulte et chez l’enfant. Rev Med Suisse 013:872–877
Spahr L, Morard I, Hadengue A, Vadas L, Pugin J (2001) Procalcitonin is not an accurate marker of spontaneous bacterial peritonitis in patients with cirrhosis. Hepatogastroenterology 48:502–505
Samama M-M, Germain D, Kamoun P, Collectif (2008) Précis de Biopathologie: Analyses médicales spécialisées. Biomnis, Lyon