Main Article Content
Abstract
RÉSUMÉ
Purple urine bag syndrome (PUBS) is a sign of urinary infection characterized by a purple staining of the urinary catheter and the urine collector by pigments resulting from the degradation of dietary tryptophan by intestinal and urinary bacteria. It is a benign syndrome but can manifest itself with complications under certain conditions. We report a case of PUBS revealed by a state of septic shock. A patient HM with a history of high blood pressure (hypertension) and stroke with left hemiplegia, bedridden for the last six months was admitted to internal medicine for her bedridden condition, anorexia, and significant weight loss. Twelve days after admission, her clinical condition deteriorated with the onset of septic shock and a change in the urine bag colour to purple. The urinary strip showed a urinary pH at 8.3, leukocyturia (2+) with nitrite (1+) and proteinuria (2+). Urine cytobacteriological examination showed leucocyturia > 104/ml, bacteriuria > 105uF/ml and the presence of K.pneumoniae sensitive to ceftriaxone. Management was based on antibiotic therapy and medical resuscitation. The patient died during resuscitation. Although PUBS is considered benign, the clinician should keep in mind the existence of life-threatening severe forms.
ABSTRACT
Le syndrome du sac urinaire violet (PUBS) est un signe d'infection urinaire caractérisé par une coloration violette de la sonde urinaire et du collecteur d'urine par des pigments résultant de la dégradation du tryptophane alimentaire par des bactéries intestinales et urinaires. Il s'agit d'un syndrome bénin mais qui peut se manifester par des complications dans certaines conditions. Nous rapportons un cas de PUBS révélé par un état de choc septique. Une patiente HM ayant des antécédents d'hypertension et d'accident vasculaire cérébral avec hémiplégie gauche, alitée depuis six mois, a été admise en médecine interne pour son état alité, son anorexie et sa perte de poids importante. Douze jours après son admission, son état clinique s'est détérioré avec l'apparition d'un choc septique et un changement de couleur de la poche d'urine qui est passée au violet. La bandelette urinaire montrait un pH urinaire de 8,3, une leucocyturie (2+) avec nitrite (1+) et une protéinurie (2+). L'examen cytobactériologique des urines a montré une leucocyturie > 104/ml, une bactériurie > 105uF/ml et la présence de K.pneumoniae sensible à la ceftriaxone. La prise en charge a été basée sur l'antibiothérapie et la réanimation médicale. Le patient est décédé pendant la réanimation. Bien que le PUBS soit considéré comme bénin, le clinicien doit garder à l'esprit l'existence de formes graves potentiellement mortelles.
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References
- Abubacker NRT, Jayaraman SMT, Kannan R, Sivanesan MK, Mathew R. Purple urine bag syndrome. Journal of clinical and diagnostic research: JCDR. 2015;9(8):OD01.
- Karray O, Batti R, Talbi E, Ayed H, Chakroun M, Ouarda MA, et al. Purple urine bag syndrome, a disturbing urine discoloration. Urology case reports. 2018;20:57.
- Hadano Y, Shimizu T, Takada S, Inoue T, Sorano S. An update on purple urine bag syndrome. International journal of general medicine. 2012;5:707.
- Su Y-J, Yang H-W. Risk factors of mortality in patients with purple urine bag syndrome. Journal of drug assessment. 2019;8(1):21–4.
- Lin J, Hlafka M, Vargas O, Bhattarai M. Recurrent purple urine bag syndrome presenting with full spectrum of disease severity: case report and review of literature. CEN case reports. 2016;5(2):144–7.
- Khan F, Chaudhry MA, Qureshi N, Cowley B. Purple urine bag syndrome: an alarming hue? A brief review of the literature. International journal of nephrology. 2011;2011.
- Worku DA. Purple urine bag syndrome: An unusual but important manifestation of urinary tract infection. Case report and literature review. SAGE open medical case reports. 2019;7:2050313X18823105.
- García-López M, Cárceles-García C, Ovsepyan M, Llenas-García J. Doctor: Why Has Her Urine Turned Purple? European journal of case reports in internal medicine. 2016;3(7).
- Richardson-May J. Single case of purple urine bag syndrome in an elderly woman with stroke. BMJ case reports. 2016;2016:bcr2016215465.
- Bhattarai M, Bin Mukhtar H, Davis TW, Silodia A, Nepal H. Purple urine bag syndrome may not be benign: a case report and brief review of the literature. Case reports in infectious diseases. 2013;2013.
- Restuccia MR, Blasi M. A PUBS Case in a Palliative Care Unit Experience. Case reports in oncological medicine. 2014;2014.
- Agapakis DI, Massa EV, Hantzis I, Paschoni E, Satsoglou E. Purple urine bag syndrome: a case report of an alarming phenomenon. Hippokratia. 2014;18(1):92.
- Wong YWE, Abdullah N. Purple urine bag syndrome: A startling phenomenon of purple urine in a urine drainage bag. A primary care approach and literature review. Malaysian family physician: the official journal of the Academy of Family Physicians of Malaysia. 2018;13(2):42.
- Traynor BP, Pomeroy E, Niall D. Purple urine bag syndrome: a case report and review of the literature. Oxford medical case reports. 2017;2017(11):omx059.
- Mumoli N, Vitale J, Brondi B, Basile V, Cei M. Purple urine-bag syndrome in a department of
- medicine
- Lee K-G, Tan C-S. An elderly nursing home resident with unusual urine bag discoloration. Nephrology Dialysis Transplantation Plus. 2011;4(6):445–6.
- Faridi MS, Rahman MJ, Mibang N, Shantajit N, Somarendra K. Purple urine bag syndrome-an alarming situation. Journal of clinical and diagnostic research: JCDR. 2016;10(2):PD05.
- Llah ST, Salman Khan AD, Morrison AJA, Jain S, Hermanns D. A case of purple urine bag syndrome in a spastic partial quadriplegic male. Cureus. 2016;8(4).
- Van Keer J, Detroyer D, Bammens B. Purple urine bag syndrome in two elderly men with urinary tract infection. Case reports in nephrology. 2015;2015.
- Koçoğlu H, Yıldırım B, Okuturlar Y, Hurşitoğlu M, Harmankaya Ö. Purple Urine Bag Syndrome in a Male Patient with Chronic Hemodialysis. Balkan medical journal. 2016;33(6):717–8.
- Karim A, Abed F, Bachuwa G. A unilateral purple urine bag syndrome in a patient with bilateral nephrostomy tubes. Case Reports. 2015;2015:bcr2015212913.
- Worku DA. Purple urine bag syndrome: An unusual but important manifestation of urinary tract infection. Case report and literature review. SAGE open medical case reports. 2019;7:2050313X18823105.
- Dealler SF, Hawkey PM, Millar MR. Enzymatic degradation of urinary indoxyl sulfate by Providencia stuartii and Klebsiella pneumoniae causes the purple urine bag syndrome. Journal of clinical microbiology. 1988;26(10):2152–6.
- Dilraj S, Joel W, Regent L, et al . Purple Urine Bag Syndrome: A Rare Spot Diagnosis.Disease Markers.2017 ;2017 :1-6
- Lazimy Y, Delotte J, Machiavello J-C, Lallement M, Imbenotte M, Bongain A. A propos d’un cas du syndrome des urines violettes. Progrès en Urologie. 2007;17(4):864–5.
- Tasi YM, Huang MS, Yang CJ, et al. Purple urine bag syndrome,not always a benign process. Am J Emerg Med. 2009;27:895–897
References
Abubacker NRT, Jayaraman SMT, Kannan R, Sivanesan MK, Mathew R. Purple urine bag syndrome. Journal of clinical and diagnostic research: JCDR. 2015;9(8):OD01.
Karray O, Batti R, Talbi E, Ayed H, Chakroun M, Ouarda MA, et al. Purple urine bag syndrome, a disturbing urine discoloration. Urology case reports. 2018;20:57.
Hadano Y, Shimizu T, Takada S, Inoue T, Sorano S. An update on purple urine bag syndrome. International journal of general medicine. 2012;5:707.
Su Y-J, Yang H-W. Risk factors of mortality in patients with purple urine bag syndrome. Journal of drug assessment. 2019;8(1):21–4.
Lin J, Hlafka M, Vargas O, Bhattarai M. Recurrent purple urine bag syndrome presenting with full spectrum of disease severity: case report and review of literature. CEN case reports. 2016;5(2):144–7.
Khan F, Chaudhry MA, Qureshi N, Cowley B. Purple urine bag syndrome: an alarming hue? A brief review of the literature. International journal of nephrology. 2011;2011.
Worku DA. Purple urine bag syndrome: An unusual but important manifestation of urinary tract infection. Case report and literature review. SAGE open medical case reports. 2019;7:2050313X18823105.
García-López M, Cárceles-García C, Ovsepyan M, Llenas-García J. Doctor: Why Has Her Urine Turned Purple? European journal of case reports in internal medicine. 2016;3(7).
Richardson-May J. Single case of purple urine bag syndrome in an elderly woman with stroke. BMJ case reports. 2016;2016:bcr2016215465.
Bhattarai M, Bin Mukhtar H, Davis TW, Silodia A, Nepal H. Purple urine bag syndrome may not be benign: a case report and brief review of the literature. Case reports in infectious diseases. 2013;2013.
Restuccia MR, Blasi M. A PUBS Case in a Palliative Care Unit Experience. Case reports in oncological medicine. 2014;2014.
Agapakis DI, Massa EV, Hantzis I, Paschoni E, Satsoglou E. Purple urine bag syndrome: a case report of an alarming phenomenon. Hippokratia. 2014;18(1):92.
Wong YWE, Abdullah N. Purple urine bag syndrome: A startling phenomenon of purple urine in a urine drainage bag. A primary care approach and literature review. Malaysian family physician: the official journal of the Academy of Family Physicians of Malaysia. 2018;13(2):42.
Traynor BP, Pomeroy E, Niall D. Purple urine bag syndrome: a case report and review of the literature. Oxford medical case reports. 2017;2017(11):omx059.
Mumoli N, Vitale J, Brondi B, Basile V, Cei M. Purple urine-bag syndrome in a department of
medicine
Lee K-G, Tan C-S. An elderly nursing home resident with unusual urine bag discoloration. Nephrology Dialysis Transplantation Plus. 2011;4(6):445–6.
Faridi MS, Rahman MJ, Mibang N, Shantajit N, Somarendra K. Purple urine bag syndrome-an alarming situation. Journal of clinical and diagnostic research: JCDR. 2016;10(2):PD05.
Llah ST, Salman Khan AD, Morrison AJA, Jain S, Hermanns D. A case of purple urine bag syndrome in a spastic partial quadriplegic male. Cureus. 2016;8(4).
Van Keer J, Detroyer D, Bammens B. Purple urine bag syndrome in two elderly men with urinary tract infection. Case reports in nephrology. 2015;2015.
Koçoğlu H, Yıldırım B, Okuturlar Y, Hurşitoğlu M, Harmankaya Ö. Purple Urine Bag Syndrome in a Male Patient with Chronic Hemodialysis. Balkan medical journal. 2016;33(6):717–8.
Karim A, Abed F, Bachuwa G. A unilateral purple urine bag syndrome in a patient with bilateral nephrostomy tubes. Case Reports. 2015;2015:bcr2015212913.
Worku DA. Purple urine bag syndrome: An unusual but important manifestation of urinary tract infection. Case report and literature review. SAGE open medical case reports. 2019;7:2050313X18823105.
Dealler SF, Hawkey PM, Millar MR. Enzymatic degradation of urinary indoxyl sulfate by Providencia stuartii and Klebsiella pneumoniae causes the purple urine bag syndrome. Journal of clinical microbiology. 1988;26(10):2152–6.
Dilraj S, Joel W, Regent L, et al . Purple Urine Bag Syndrome: A Rare Spot Diagnosis.Disease Markers.2017 ;2017 :1-6
Lazimy Y, Delotte J, Machiavello J-C, Lallement M, Imbenotte M, Bongain A. A propos d’un cas du syndrome des urines violettes. Progrès en Urologie. 2007;17(4):864–5.
Tasi YM, Huang MS, Yang CJ, et al. Purple urine bag syndrome,not always a benign process. Am J Emerg Med. 2009;27:895–897