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RÉSUMÉ
Objectif. Décrire les caractéristiques épidémiologiques, cliniques, thérapeutiques et évolutives des occlusions sur carcinose péritonéale dans 3 hôpitaux de référence de Douala et Yaoundé. Méthodologie. Nous avons mené une étude descriptive rétrospective du 1er janvier 2017 au 31 Décembre 2021 (5 ans) à partir des dossiers cliniques des patients diagnostiqués d’une occlusion sur carcinose péritonéale dans les services d’oncologie et de chirurgie viscérale de 3 hôpitaux de référence des villes de Douala et Yaoundé. Les variables étudiées étaient les données sociodémographiques, cliniques et paracliniques, thérapeutiques et évolutives. Résultats. Sur 12 553 dossiers dépouillés, 243 (1,93%) cas d’occlusions intestinales ont été répertoriés et parmi eux 37 (15,22%) étaient des occlusions sur carcinose péritonéale, dont 6 ont été exclus pour informations incomplètes. L’âge moyen était de 54,22 (±18) ans, avec une prédominance féminine (18 ; 58,06%). Les cancers primitifs les plus retrouvés étaient le cancer colorectal (45,15%) et le cancer de l’ovaire (19,35%). Les manifestations cliniques les plus retrouvées étaient la douleur abdominale (100%) et l’arrêt des matières et des gaz (90,32%). L’occlusion était basse dans 70,96% des cas. Le traitement médical était l’option thérapeutique la plus utilisée dans 64,52% des cas. La médiane de survie était de 3,26 mois. Il n’y avait pas d’association significative entre la survie et le type de traitement utilisé. Conclusion. Les occlusions sur carcinose péritonéale représentent 15% des occlusions intestinales dans notre contexte. La survie globale n’est pas associée au type de traitement.
ABSTRACT
Objective. To report the epidemiological, clinical, therapeutic and evolutionary characteristics of bowel obstructions due to peritoneal carcinomatosis in 3 referral hospitals in Douala and Yaoundé. Methodology. We conducted a retrospective analytical study from January 1er 2017 to December 31 2021 (5 years) based on the clinical records of patients diagnosed with Bowel obstructions due to peritoneal carcinomatosis in the oncology and visceral surgery departments of 3 referral hospitals in the cities of Douala and Yaoundé. The variables studied were socio-demographic, clinical and paraclinical, therapeutic and evolutionary data. Results. 243 (1.93%) cases of Bowel obstruction were identified out of 12,553 records. Of these, 37 (15.22%) were obstructions due to peritoneal carcinosis, 6 of which were excluded for incomplete information. The mean age was 54.22 (±18) years, with a female predominance (18; 58.06%). The most common primary cancers were colorectal (45.15%) and ovarian (19.35%). The most common clinical manifestations were abdominal pain (100%) and cessation of bowel movements and gas (90.32%). Occlusion was low in 70.96% of cases. Medical treatment was the most commonly used therapeutic option in 64.52% of cases. Median survival was 3.26 months. There was no significant association between survival and the type of treatment used. Conclusion. Occlusions due to peritoneal carcinosis account for 15% of intestinal occlusions in our setting. Overall survival is not associated with the type of treatment.

Keywords

Occlusion peritoneal carcinosis treatment survival curve Occlusion carcinose péritonéale traitement courbe de survie

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Dina Bell Esther Hortense Murielle, Ntama Ambroise, Esson Mapoko BS, Sango Anne, Ekwa Langa Dominique, Atenguena Etienne, Anne Marthe Maïson Mayeh, Ruth Meka’ah Mapenya, Anaba Dominique, Ndangue Ntone, Mouelle Mbassi, Mouelle Michel, Ananga Noa Sidonie, Albert Mouelle Sone, Paul Ndom, & Eboumbou Moukoko. (2024). Bowel Occlusions on Peritoneal Carcinosis: Epidemioclinical Features, Management and Outcome in Referral Hospitals of Douala and Yaoundé: Occlusions sur Carcinose Péritonéale : Caractéristiques Épidémiocliniques, Thérapeutiques et Évolutives dans les Hôpitaux de Référence de Douala et Yaoundé. HEALTH SCIENCES AND DISEASE, 25(5). https://doi.org/10.5281/hsd.v25i5.5655
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