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Abstract
RÉSUMÉ
Introduction. La survenue d’une infection du site opératoire (ISO) en chirurgie orthopédique et traumatologique est une véritable catastrophe qui peut ruiner le bénéfice d’une intervention. Ce travail avait pour but de déterminer l’incidence et les facteurs prédictifs de survenue des ISO en chirurgie orthopédique et traumatologique propre à Yaoundé. Patients et méthodes. Nous avons réalisé une étude de cohorte prospective multicentrique. Tous les patients âgés de 18 ans ou plus, admis pour une chirurgie orthopédique et traumatologique de classe 1 d’Altemeier, du 1er janvier au 30 juin 2023, dans 4 hôpitaux universitaires de Yaoundé, étaient inclus dans cette étude. Les patients ont été suivis jusqu’à J30 postopératoire à la recherche d’une ISO définie selon les critères CDC (Centers for Disease Control and Prevention) 2018. Une analyse multivariée par régression logistique binaire a été utilisée pour rechercher les facteurs prédictifs de survenue d’ISO. Résultats. Au total 253 patients ont été inclus dans l’étude, dont 156 (61.7%) étaient des hommes, pour un âge moyen de 44,4 ± 16,5 ans. L’ostéosynthèse interne des fractures (83,4%) et les arthroplasties (11,0%) étaient les principales indications chirurgicales. L’incidence des ISO était de 9,5%. En analyse multivariée, le seul facteur prédictif indépendant d’une ISO était la survenue d’une fièvre post opératoire (aOR=0,052 ; IC à 95% : 0,003-0,0887 ; p= 0,041). Conclusion. Malgré les progrès observés en chirurgie orthopédique et traumatologique propre dans notre environnement, l’incidence de l’ISO reste relativement élevée. Une fièvre survenant à partir du 5ème jour postopératoire est un facteur prédictif indépendant d’ISO.
ABSTRACT
Introduction. The occurrence of a surgical site infection (SSI) in orthopedic and trauma surgery is a disaster that can ruin the benefit of an intervention. This study aimed to determine the incidence and predictive factors for the occurrence of SSI in clean orthopedic and trauma surgery in Yaoundé. Patients and methods. We carried out a prospective multicenter cohort study. All patients aged 18 years or older, admitted for Altemeier class 1 orthopedic and trauma surgery, from January 1 to June 30, 2023, in 4 university teaching hospitals in Yaoundé, were included in this study. The patients were followed-up until postoperative day 30 for SSI defined according to the CDC (Centers for Disease Control and Prevention) 2018 criteria. A multivariate logistic regression was used to determine the predictive factors for the occurrence of SSI. Results. A total of 253 patients were included in the study, of whom 156 (61.7%) were men, for a mean age of 44.4±16.5 years. Internal fixation of fractures (83.4%) and arthroplasties (11.0%) were the main surgical indications. The incidence of SSI was 9.5%. The average time to occurrence of SSI was 12.5 ± 9.5 days. In multivariate analysis, the only independent predictive factor of SSI was the presence of postoperative fever (aOR = 0.052; 95% CI: 0.003-0.0887; p = 0.041). Conclusion. Despite the progress observed in clean orthopedic and trauma surgery in our environment, the incidence of SSI remains relatively high. A fever occurring in the postoperative period is an independent predictor of SSI.
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References
- Mokdad AH, Forouzanfar MH, Daoud F, et al. Global burden of diseases, injuries, and risk factors for young people’s health during 1990–2013: A systematic analysis for the Global Burden of Disease Study 2013. The Lancet 2016; 387:2383–2401.
- McQuillan TJ, Cai LZ, Corcoran-Schwartz I, Weiser TG, Forrester JD. Surgical Site Infections after Open Reduction Internal Fixation for Trauma in Low and Middle Human Development Index Countries: A Systematic Review. Surgical infections 2018; 19(3):254-263
- Whitehouse JD, Friedman ND, Kirkland KB, et al. The impact of surgical-site infections following orthopedic surgery at a community hospital and a university hospital:Adverse quality of life, excess length of stay, and extracost. Infect Control Hosp Epidemiol 2002;23:183–189.
- Sun Y, Wang H, Tang Y et al. Incidence and risk factors for surgical site infection after open reduction and internal fixation of ankle fracture A retrospective multicenter study. Medicine 2018; 97:7(e9901)
- Tucci G, Romanini E, Zanoli G, Pavan L, Fantoni M, Venditti M. Prevention of surgical site infections in orthopaedic surgery: a synthesis of current recommendations. European Review for Medical and Pharmacological Sciences 2019; 23(2 Suppl.): 224-239
- World Health Organization (WHO) Global guidelines on the prevention of surgical site infection, November 2016. http://who.int/gpsc/ssi-prevention-guidelines/en/ (accessed October 2018).
- Healthcare Infection Control Practices Advisory Committee (HIC-PAC). Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, May 2017. https://www.cdc.gov/infectioncontrol/guidelines/ssi/index.html (accessed October 2018).
- National Institute for Health and Care Excellence (NICE). Surgical site infections: prevention and treatment. Clinical Guideline CG74, October 2008, last update February 2017. https://www.nice.org. uk/guidance/cg74 (accessed October 2018)
- Gosselin RA, Charles A, Joshipura M, et al. Surgery and trauma care. In: Debas HT, Donkor P, Gawande A, et al. (eds.) Essential Surgery. Disease Control Priorities, Third edition, Volume 1. Washington, DC: World Bank. 2015:41.
- Todd B. New CDC Guideline for the Prevention of Surgical Site Infection. Am J Nurs 2017;117(8):17
- Lu K, Zhang J, Cheng J, et al. Incidence and risk factors for surgical site infection after open reduction and internal fixation of intraarticular fractures of distal femur: A multicentre study. Int Wound J. 2019;16:473–478.
- Horan TC, Gaynes RP, Martone WJ, Jarvis WR, Emori TG. CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections. Infect Control Hosp Epidemiol. 1992;13(10):606-608.
- Ayouba G, Bakriga B, Dellanah, Kombate NK. Infection sur matériel d’ostéosynthése en orthopédie:Problématique de la prise en charge au CHU Sylvanius Olympio de Lomé. Health Science Disease 2022; 23(6) :77-81
- Idé, G., Abdoul Wahab, M., Hama, Y., Habibou, D., & Hans-Moevi, A. L’Infection du Site Opératoire en Chirurgie Ortho-Traumatologique Propre au CNHU-HKM de Cotonou. Health Sciences and Disease 2018; 19(2).
- Abalo A, Walla A, Ayouba G, Ndjam M, Agounké W, Dossim A Surgical site infection (SSI) in orthopaedics’ patients in a developing country. Revue de chirurgie orthopédique et traumatologique 2010;96:112—117
- Kisibo A, Ndume VA, Semiono A, Mika E, Sariah A, Protas J, Landolin H. Surgical Site Infection among Patients Undergone Orthopaedic Surgery at Muhimbili Orthopaedic Institute, Dar es Salaam, Tanzania. East & Central African Journal of Surgery 2017; 22 (1):49-58
- Bercion R, Gaudeuille A, Mapouka PA, Behounde T, Guetahoun Y. Chirurgical site infection survey in the orthopaedics surgery department of the ‘‘Hôpital communautaire de Bangui’’ Central African Republic. Bull Soc Pathol Exot 2007; 100(3) :197-200
- Tékpa BJD, Tékpa G, Mapouka PAI, Djimong-Manda CD, Ngbangbangaï E, Koffi B. La prévention des infections du site opératoire en orthopédie dans un pays en voie de développement. Revue de chirurgie orthopédique et traumatologique 2017;103(7):823-87
- Shao, J, Zhang, H, Yin, B, Li, J, Zhu, Y, Zhang, Y. Risk factors for surgical site infection following operative treatment of ankle fractures: A systematic review and meta-analysis
- Int J Surg 2018;56 :124-132
- Li, J, Zhu, Y, Liu, B, Dong, T, Chen, W, Zhang, Y. Incidence and risk factors for surgical site infection following open reduction and internal fixation of adult tibial plateau fractures. Int Orthop 2018;42(6) :1397-1403
- Ewelina Kocur, Piotr Rozentryt, Anna Głogowska-Gruszka. Risk factors for surgical site infection in patients after implant-related orthopedic procedures. Przegl Epidemiol. 2021;75(3):332-346.
- Cissoko AS, Touré M, Dembélé B, Sidibé N et al. 2022. L’hypertension artérielle du sujet âgé au CHU Gabriel Touré (Bamako). Health sciences and Diesease,23(8).
References
Mokdad AH, Forouzanfar MH, Daoud F, et al. Global burden of diseases, injuries, and risk factors for young people’s health during 1990–2013: A systematic analysis for the Global Burden of Disease Study 2013. The Lancet 2016; 387:2383–2401.
McQuillan TJ, Cai LZ, Corcoran-Schwartz I, Weiser TG, Forrester JD. Surgical Site Infections after Open Reduction Internal Fixation for Trauma in Low and Middle Human Development Index Countries: A Systematic Review. Surgical infections 2018; 19(3):254-263
Whitehouse JD, Friedman ND, Kirkland KB, et al. The impact of surgical-site infections following orthopedic surgery at a community hospital and a university hospital:Adverse quality of life, excess length of stay, and extracost. Infect Control Hosp Epidemiol 2002;23:183–189.
Sun Y, Wang H, Tang Y et al. Incidence and risk factors for surgical site infection after open reduction and internal fixation of ankle fracture A retrospective multicenter study. Medicine 2018; 97:7(e9901)
Tucci G, Romanini E, Zanoli G, Pavan L, Fantoni M, Venditti M. Prevention of surgical site infections in orthopaedic surgery: a synthesis of current recommendations. European Review for Medical and Pharmacological Sciences 2019; 23(2 Suppl.): 224-239
World Health Organization (WHO) Global guidelines on the prevention of surgical site infection, November 2016. http://who.int/gpsc/ssi-prevention-guidelines/en/ (accessed October 2018).
Healthcare Infection Control Practices Advisory Committee (HIC-PAC). Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, May 2017. https://www.cdc.gov/infectioncontrol/guidelines/ssi/index.html (accessed October 2018).
National Institute for Health and Care Excellence (NICE). Surgical site infections: prevention and treatment. Clinical Guideline CG74, October 2008, last update February 2017. https://www.nice.org. uk/guidance/cg74 (accessed October 2018)
Gosselin RA, Charles A, Joshipura M, et al. Surgery and trauma care. In: Debas HT, Donkor P, Gawande A, et al. (eds.) Essential Surgery. Disease Control Priorities, Third edition, Volume 1. Washington, DC: World Bank. 2015:41.
Todd B. New CDC Guideline for the Prevention of Surgical Site Infection. Am J Nurs 2017;117(8):17
Lu K, Zhang J, Cheng J, et al. Incidence and risk factors for surgical site infection after open reduction and internal fixation of intraarticular fractures of distal femur: A multicentre study. Int Wound J. 2019;16:473–478.
Horan TC, Gaynes RP, Martone WJ, Jarvis WR, Emori TG. CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections. Infect Control Hosp Epidemiol. 1992;13(10):606-608.
Ayouba G, Bakriga B, Dellanah, Kombate NK. Infection sur matériel d’ostéosynthése en orthopédie:Problématique de la prise en charge au CHU Sylvanius Olympio de Lomé. Health Science Disease 2022; 23(6) :77-81
Idé, G., Abdoul Wahab, M., Hama, Y., Habibou, D., & Hans-Moevi, A. L’Infection du Site Opératoire en Chirurgie Ortho-Traumatologique Propre au CNHU-HKM de Cotonou. Health Sciences and Disease 2018; 19(2).
Abalo A, Walla A, Ayouba G, Ndjam M, Agounké W, Dossim A Surgical site infection (SSI) in orthopaedics’ patients in a developing country. Revue de chirurgie orthopédique et traumatologique 2010;96:112—117
Kisibo A, Ndume VA, Semiono A, Mika E, Sariah A, Protas J, Landolin H. Surgical Site Infection among Patients Undergone Orthopaedic Surgery at Muhimbili Orthopaedic Institute, Dar es Salaam, Tanzania. East & Central African Journal of Surgery 2017; 22 (1):49-58
Bercion R, Gaudeuille A, Mapouka PA, Behounde T, Guetahoun Y. Chirurgical site infection survey in the orthopaedics surgery department of the ‘‘Hôpital communautaire de Bangui’’ Central African Republic. Bull Soc Pathol Exot 2007; 100(3) :197-200
Tékpa BJD, Tékpa G, Mapouka PAI, Djimong-Manda CD, Ngbangbangaï E, Koffi B. La prévention des infections du site opératoire en orthopédie dans un pays en voie de développement. Revue de chirurgie orthopédique et traumatologique 2017;103(7):823-87
Shao, J, Zhang, H, Yin, B, Li, J, Zhu, Y, Zhang, Y. Risk factors for surgical site infection following operative treatment of ankle fractures: A systematic review and meta-analysis
Int J Surg 2018;56 :124-132
Li, J, Zhu, Y, Liu, B, Dong, T, Chen, W, Zhang, Y. Incidence and risk factors for surgical site infection following open reduction and internal fixation of adult tibial plateau fractures. Int Orthop 2018;42(6) :1397-1403
Ewelina Kocur, Piotr Rozentryt, Anna Głogowska-Gruszka. Risk factors for surgical site infection in patients after implant-related orthopedic procedures. Przegl Epidemiol. 2021;75(3):332-346.
Cissoko AS, Touré M, Dembélé B, Sidibé N et al. 2022. L’hypertension artérielle du sujet âgé au CHU Gabriel Touré (Bamako). Health sciences and Diesease,23(8).